Results 71 to 80 of about 1,227,803 (177)

A decline of protective apolipoprotein J and complement factor H concomitant with increase in C5a 3 months after cardiac surgery—Evidence of long-term complement perturbations

Frontiers in Cardiovascular Medicine, 2022
BackgroundHeart surgery results in complement activation with the potential for collateral end-organ damage, especially if the protective elements (complement factor H, Apolipoprotein J) are inadequate. Here, we have investigated if peri-operative stress
Krzysztof Laudanski, Krzysztof Laudanski, Krzysztof Laudanski, Da Liu, Damodar Gullipalli, Wen-Chao Song, Tony Okeke, Wilson Y. Szeto   +7 more
doaj   +1 more source

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency [PDF]

, 2008
Atypical hemolytic uremic syndrome (aHUS) is a severe renal disease that is associated with defective complement regulation caused by multiple factors.
Józsi, Mihály, Licht, C., Richter, H., Strobel, S., Zipfel, S. L.   +4 more
core   +1 more source

Estimation of interdomain flexibility of N-terminus of factor H using residual dipolar couplings [PDF]

, 2011
Characterization of segmental flexibility is needed to understand the biological mechanisms of the very large category of functionally diverse proteins, exemplified by the regulators of complement activation, that consist of numerous compact modules or ...
Apic G., Barlow P. N., Barlow P. N., Bernadó P., Bertini I., Bertini I., Bertini I., Bork P., Chen K., Clore G. M., Clore G. M., Clore G. M., Cornilescu G., Delaglio F., DiScipio R. G., Ekman D., Fernando A. N., Ferreira V. P., Furtado P. B., Garrett D. S., Gordon D. L., Henderson C. E., Hocking H. G., Hoebe K., Hourcade D., Janssen B. J. C., Kirkitadze M. D., Kirkitadze M. D., Kirkitadze M. D., Kirkitadze M. D., Lachmann P. J., Lakomek N.-A., Laskowski R. A., Lipari G., Litman G. W., Longinetti M., Losonczi J., Mateusz Maciejewski, McRee D. E., Meiler J., Morgan H. P., Nico Tjandra, Norman D. G., Okemefuna A. I., Okemefuna A. I., Ottiger M., Paul N. Barlow, Reid K., Ricklin D., Schmidt C. Q., Schwieters C. D., Schwieters C. D., Soares D. C., Soares D. C., Tjandra N., Tolman J. R., Ulrich E. L., Vranken W. F., Walport M. J., Weisman H. F., Wu J.   +60 more
core   +1 more source

Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement [PDF]

, 2004
The complement system is important in immunosurveillance against tumors. However, malignant cells are usually resistant to complement-mediated lysis. In this study, we examine the expression of factor H, an inhibitor of complement activation, and factor ...
Ajona, D. (Daniel), Castaño, Z. (Z.), Cuttitta, F. (Frank), Garayoa, M. (Mercedes), Martinez, A. (Alfredo), Montuenga-Badia, L.M. (Luis M.), Pajares, M.J. (María José), Pio, R. (Rubén), Zudaire, E. (Enrique)   +8 more
core  

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]

, 1986
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Barranco, Brenner, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, González-Fernández, Hens, Kihlman, Kihlman, Kihlman, Kihlman, Lau, Lehmann, Moreno, Nilsson, Painter, Painter, Raith, Rappold, Roberts, Schardin, Sedgwick, Setlow, Stack, Steward, Tatsumi, Tobey, Tomulin, Zorn, Zorn   +42 more
core   +1 more source

Complement factor H gene polymorphisms and vivax malaria associated thrombotic microangiopathy

Saudi Journal of Kidney Diseases and Transplantation, 2019
Acute kidney injury (AKI) occurs in about 1% of cases of malaria; however, in these cases, the mortality rate can be as high as 45%. Thrombotic microangiopathy (TMA) as a cause of AKI in malaria is rare with only a handful cases documented in literature ...
Parimal Agrawal, Ashwani Kumar, Amber Parwaiz, Amit Rawat, Karalanglin Tiewsoh, Ritambhra Nada   +5 more
doaj   +1 more source

Polyanion-Induced Self-Association of Complement Factor H [PDF]

The Journal of Immunology, 2009
Abstract Factor H is the primary soluble regulator of activation of the alternative pathway of complement. It prevents activation of complement on host cells and tissues upon association with C3b and surface polyanions such as sialic acids, heparin, and other glycosaminoglycans.
Michael K, Pangburn, Nenoo, Rawal, Claudio, Cortes, M Nurul, Alam, Viviana P, Ferreira, Mark A L, Atkinson   +5 more
openaire   +2 more sources

Urine Complement Proteins and the Risk of Kidney Disease Progression and Mortality in Type 2 Diabetes. [PDF]

, 2018
ObjectiveWe examined the association of urine complement proteins with progression to end-stage renal disease (ESRD) or death in people with type 2 diabetes and proteinuric diabetic kidney disease (DKD).Research design and methodsUsing targeted mass ...
Afkarian, Maryam, Babenko, Ilona, Durbin-Johnson, Blythe, Mehrotra, Rajnish, Rocke, David M, Vaisar, Tomas, Whitlock, Kathryn   +6 more
core   +1 more source

Integration of an Active Filter and a Single-Phase AC/DC Converter with Reduced Capacitance Requirement and Component Count [PDF]

, 2015
Existing methods of incorporating an active filter into an AC/DC converter for eliminating electrolytic capacitors usually require extra power switches. This inevitably leads to an increased system cost and degraded energy efficiency.
Hui, SYR, Li, S, Qi, W, Tan, SC
core   +1 more source

Complement Factor H Polymorphism p.Tyr402His and Cuticular Drusen [PDF]

Archives of Ophthalmology, 2007
To determine the histidine frequency in patients with the cuticular drusen phenotype of age-related macular degeneration (AMD).Fifty individuals were identified who met the criteria for the cuticular drusen phenotype using a standard threshold photograph. We genotyped DNA samples using a polymerase chain reaction-based restriction digest assay.
Michael A, Grassi, James C, Folk, Todd E, Scheetz, Christine M, Taylor, Val C, Sheffield, Edwin M, Stone   +5 more
openaire   +2 more sources