Results 201 to 210 of about 93,626 (282)

The Complement System in ANCA-Associated Vasculitis: Mechanistic Insights, Therapeutic Horizons, and Unmet Clinical Needs. [PDF]

Immun Inflamm Dis
Sunmboye K, Millan P.
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Update in the diagnosis of complement-mediated thrombotic microangiopathy/atypical hemolytic uremic syndrome. [PDF]

Hematology Am Soc Hematol Educ Program
Cole MA.
europepmc   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

Advanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green, Michael W. Jones, Merissa Saleem, Haobo Ge, Melita Tvardauskaite, Julia Dudzic, Fernando Cortezon‐Tamarit, Rory L. Arrowsmith, Charareh Pourzand, Gabriele Kociock‐Kohn, Nicholas H. Rees, Jonathan R. Dilworth, Stephen Faulkner, Stanley W. Botchway, David Gurevich, Sofia I. Pascu   +15 more
wiley   +1 more source

Complement role in kidney disease: a comprehensive review and therapeutic innovations. [PDF]

BMC Nephrol
Cortez Ferreira B, Matos Silva G, Venda J, Afonso N, Leal R, Cerqueira S, Galvão A, Sá H.   +7 more
europepmc   +1 more source

Detection of a Soluble Form of the Complement Membrane Attack Complex Inhibitor CD59 in Plasma after Acute Myocardial Infarction

Scandinavian Journal of Immunology, 2000
A. Väkevä, T. Lehto, A. Takala, A. Takala, Seppo Meri   +4 more
semanticscholar   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Complement system in cancer: friend or foe of immunotherapy. [PDF]

J Immunother Cancer
Shah HK, Prem S, Wu X, Liszewski MK, Atkinson JP, Singh AK, Kapoor V.   +6 more
europepmc   +1 more source

Mullins' syndrome: a new gammopathy-related autoinflammatory syndrome resistant to anakinra [PDF]

, 2015
A.L. Manson, Arend, Gekowski, H.J. Longhurst, Haeffner-Cavaillon, J.D. Cavenagh, M.S. Buckland, Nashan, Okusawa, P.F.K. Yong, Rybojad, S. Grigoriadou, Schindler   +12 more
core   +1 more source