Results 61 to 70 of about 80,513 (156)

Detection and characterisation of Complement protein activity in bovine milk by bactericidal sequestration assay [PDF]

, 2015
Susan Maye is in receipt of a Teagasc Walsh Fellowship. Financial support by the Department of Agriculture, Food and the Marine is gratefully acknowledged.Copyright © Proprietors of Journal of Dairy Research 2015 (Institute of Food Research and the ...
Fitzgerald, Gerald F, Kelly, Philip, Maye, Susan, STANTON, CATHERINE   +3 more
core   +1 more source

Membrane Attack Complex and Factor H in Humans with Acute Kidney Injury

Kidney & Blood Pressure Research, 2018
Background and Aims: Complement system seems to play an important role in the pathogenesis of Acute Kidney Injury (AKI). The aim of this study was to investigate the role of complement system in the pathogenesis of human AKI. For this purpose, we studied
Eva Rodríguez, Javier Gimeno, Carlos Arias-Cabrales, Clara Barrios, Dolores Redondo- Pachón, María José Soler, Marta Crespo, Adriana Sierra-Ochoa, Marta Riera, Julio Pascual   +9 more
doaj   +1 more source

Complement membrane attack and tumorigenesis: a systems biology approach [PDF]

, 2016
Tumor development driven by inflammation is now an established phenomenon, but the role that complement plays remains uncertain. Recent evidence has suggested that various components of the complement (C) cascade may influence tumor development in ...
Acharyya, Ahmad, Badea, Beadling, Benzaquen, Bessarabova, Bjørge, Bolitho, Bolstad, Campbell, Carpenter, Castillo, Chintakuntlawar, Cole, Corrales, Cybulsky, D'Antonio, Deryugina, Egeblad, Eisenhart, Fang, Fishelson, Fleischmann, Fosbrink, Gunn, Halperin, Hanahan, Hepburn, Hila, Huang, Hänsch, James, Johnson, Johnson, Kilgore, Kudo, Kumbrink, LeJeune, Liacini, Liu, Lo, Lochter, Lucas, Lueck, Lukashev, Markiewski, Markiewski, Markiewski, Monk, Morgan, Morgia, Müller-Eberhard, Nagase, Niculescu, Niculescu, Nunn, O'Barr, Olayioye, Pio, Pio, Rubie, Rus, Rutkowski, Shen, Sternlicht, Taylor, Triantafilou, Viedt, Wagner, Wai, Walport, Wang, Yamakawa, Yang, Yee, Ytting, Zenz   +76 more
core   +1 more source

Novel mechanisms of immune evasion by Schistosoma mansoni

Memorias do Instituto Oswaldo Cruz, 1995
The interaction of Schistosoma mansoni with its host's immune system is largely affected by multiple specific and non-specific evasion mechanisms employed by the parasite to reduce the host's immune reactivity. Only little is known about these mechanisms
Zvi Fishelson
doaj   +1 more source

Hepatitis B virus suppresses complement C9 synthesis by limiting the availability of transcription factor USF-1 and inhibits formation of membrane attack complex: implications in disease pathogenesis

Journal of Biomedical Science, 2022
Background The complement system functions primarily as a first-line host defense against invading microbes, including viruses. However, the interaction of Hepatitis B virus (HBV) with the complement-components during chronic HBV infection remains ...
Ayana Baidya, Mousumi Khatun, Rajiv Kumar Mondal, Suchandrima Ghosh, Bidhan Chandra Chakraborty, Shreya Mallik, S. K. Mahiuddin Ahammed, Abhijit Chowdhury, Soma Banerjee, Simanti Datta   +9 more
doaj   +1 more source

DYNAMICS OF ACTIVITY OF SOME COMPONENTS OF COMPLEMENT IN TREATMENT OF ATOPIC DERMATITIS IN CHILDREN

Детские инфекции (Москва), 2015
The article describes immunoassay methods of determining the functional activity of the components C3 and C9 and C1 inhibitor for diagnostic and prognostic purposes in the treatment of patients.
S. S. Andina, A. M. Bichucher, N. V. Gora, L. V. Kozlov, O. V. Logunov, O. A. Bashkina, O. V. Rubalsky, A. V. Aleshkin   +7 more
doaj   +1 more source

COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]

, 1993
Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ, Mathieson, PW, Oliveria, DB, Peters, DK, Würzner, R   +4 more
core   +1 more source

Terminal complement complexes with or without C9 potentiate antimicrobial activity against Neisseria gonorrhoeae

mBio
The complement cascade is a front-line defense against pathogens. Complement activation generates the membrane attack complex (MAC), a 10–11 nm diameter pore formed by complement proteins C5b through C8 and polymerized C9. The MAC embeds within the outer
Evan R. Lamb, Alison K. Criss
doaj   +1 more source

Reduced membrane attack complex formation in umbilical cord blood during Eculizumab treatment of the mother: a case report

BMC Nephrology, 2019
Background Atypical hemolytic uremic syndrome (aHUS) is a disorder of the microvasculature with hemolytic anemia, thrombocytopenia and acute kidney injury.
Subagini Nagarajah, Martin Tepel, Christian Nielsen, Kristian Assing, Yaseelan Palarasah, Lise Lotte Torvin Andersen, Lotte Borg Lange, Claus Bistrup   +7 more
doaj   +1 more source

Renal C3 complement component: feed forward to diabetic kidney disease [PDF]

, 2015
BACKGROUND: Diabetic nephropathy is the main cause of end-stage renal disease and has reached epidemic proportions. METHODS: Comprehensive genomic profiling (RNAseq) was employed in the ZS (F1 hybrids of Zucker and spontaneously hypertensive heart ...
Dominguez, Jesus H., Kelly, Katherine J., Liu, Yunlong, Zhang, Jizhong   +3 more
core   +2 more sources