Results 121 to 130 of about 425,149 (322)

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

An alternative approach to hyperbolic structures on link complements [PDF]

open access: yesAlgebraic & Geometric Topology 14 (2014), 1307-1337, 2011
An alternative method is described for determining the hyperbolic structure on a link complement, and some of its elementary consequences are examined. The method is particularly suited to alternating links.
arxiv  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

The Functional Amyloid Curli Protects Escherichia coli against Complement-Mediated Bactericidal Activity

open access: yesBiomolecules, 2018
Escherichia coli strains may be beneficial or pathogenic. Many E. coli strains that cause human disease, especially those responsible for bacteremia and sepsis, express virulence factors that impart resistance to the complement system.
Steven G. Biesecker   +3 more
doaj   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

open access: yesFEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi   +4 more
wiley   +1 more source

Hipocomplementemia en pacientes con enfermedad de Hodgkin Hypocomplementaemia in patients with Hodgkin disease

open access: yesRevista Cubana de Hematología, Inmunología y Hemoterapia, 2003
The haemolytic activity of the classical and alternative pathways, of factors B and D, as well as of the levels of C1q, C3 and C4 was determined in the serum of 24 adult patients with Hodgkin disease at different clinical stages.
doaj  

A novel inhibitor of the alternative pathway of complement reverses inflammation and bone destruction in experimental arthritis [PDF]

open access: yes
Complement is an important component of the innate and adaptive immune response, yet complement split products generated through activation of each of the three complement pathways (classical, alternative, and lectin) can cause inflammation and tissue ...
Barck, Kai H.   +14 more
core   +2 more sources

Method, liposome collection, and kit for determining complement activity [PDF]

open access: yes
The present invention relates to a method of determining complement activity, wherein said method comprises determining classical complement pathway activity, determining alternative complement pathway activity, and/or determining lectin complement ...
Baumner, Antje   +3 more
core  

An investigation into the feasibility and efficacy of stereotactic radiosurgery for 1–3 cm single brain lesions on the ring‐mounted Halcyon LINAC

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose An evaluation of the accuracy, safety, and efficiency of the Halcyon ring delivery system (RDS) for stereotactic radiosurgery (SRS) treatment to relatively small (1–3 cm) brain lesions. Methods After completing the extensive in‐house quality assurance checks including Winston–Lutz test and independent dose verification via MD Anderson ...
Kate Hazelwood   +5 more
wiley   +1 more source

Empowering young minds through STEM education: Engaging high schoolers in Ghana through medical physics

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To promote diversity in Science, Technology, Engineering, and Mathematics (STEM), an educational presentation and hands‐on session was organised to raise awareness of STEM career opportunities among high school girls to introduce the students to the field of medical physics. Materials and Methods The study involved 65 first‐year Senior
Afua A. Yorke   +7 more
wiley   +1 more source

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