Results 241 to 250 of about 330,196 (324)

Reconfigurable Nucleic Acid Nanoparticles with Therapeutic RNAi Responses to Intracellular Disease Markers

Advanced Functional Materials, EarlyView.
Many known diseases arise from dysregulated gene expression, and differentially expressed genes can serve as biomarkers to distinguish diseased cells from healthy tissues. In this study, reconfigurable nucleic acid nanoparticles (recNANPs) are introduced that can detect overexpressed cancer biomarkers and subsequently release RNAi inducers to silence ...
Yelixza I. Avila, Anh Ha, Morgan R. Chandler, Nathalia Leal Santos, Taejin Kim, Hannah S. Newton, Marina A. Dobrovolskaia, Kirill A. Afonin   +7 more
wiley   +1 more source

Paroxysmal Nocturnal Hemoglobinuria: Unraveling Its Molecular Pathogenesis and Advancing Targeted Therapeutic Strategies. [PDF]

Diseases
Apostolidou E, Georgoulis V, Leonardos D, Kapsali E, Hatzimichael E.   +4 more
europepmc   +1 more source

Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium‐induced colitis

Clinical and Experimental Immunology, 2015
Michelle Elvington, Jennifer Schepp-Berglind, S. Tomlinson   +2 more
semanticscholar   +1 more source

Printing Nacre‐Mimetic MXene‐Based E‐Textile Devices for Sensing and Breathing‐Pattern Recognition Using Machine Learning

Advanced Functional Materials, EarlyView.
This study presents a Ti3C2Tx MXene/WPU nacre‐mimetic nanomaterial as a printable ink for direct‐write printing onto textiles‐based sensors. The resulting wearable device demonstrates high sensitivity, biocompatibility, and mechanical strength. Furthermore, NFC‐enabled humidity sensor produces time‐series data, which informs a machine learning ...
Lulu Xu, Wenqing Chen, Qian Li, Rohit Gupta, Biswajoy Bagchi, Laurence B. Lovat, Manish K. Tiwari   +6 more
wiley   +1 more source

Biocompatibility in hemodialysis: artificial membrane and human blood interactions. [PDF]

BMC Nephrol
Ávila E, Sepúlveda RA, Retamal J, Hachim D.   +3 more
europepmc   +1 more source

Essential Role of Factor B of the Alternative Complement Pathway in Complement Activation and Opsonophagocytosis during Acute Pneumococcal Otitis Media in Mice

Infection and Immunity, 2011
Qian Li, Y. Li, G. Stahl, J. Thurman, Yujuan He, H. Tong   +5 more
semanticscholar   +1 more source

Tunable Synthetic Hydrogel Modulates Hepatic Lineage Specification of Human Liver Organoid

Advanced Functional Materials, EarlyView.
In this study, a synthetic hydrogel is reported that supports the formation of hiPSC‐derived human liver organoids (HLOs). Hepatic lineage specification can be modulated via conjugation of RGD peptide to hydrogel: RGD‐conjugated hydrogels promote cholangiocyte differentiation, whereas RGD‐free hydrogels favor hepatocyte commitment of HLO cells.
Lei Wang, Lasse Riediger, Qi Rao, Xun Xu, Yan Nie, Yiduo Zhou, Junyao Zhang, Peng Tang, Weiwei Wang, Frank Tacke, Adrien Guillot, Ludovic Vallier, Irene Talon, Wenzhong Li, Yi‐An Yang, Rainer Haag, Nan Ma   +16 more
wiley   +1 more source

Novel Evasion Mechanisms of the Classical Complement Pathway

Journal of Immunology, 2016
B. Garcia, S. Zwarthoff, S. Rooijakkers, B. Geisbrecht   +3 more
semanticscholar   +1 more source

Artificial Intelligence‐Driven Development in Rechargeable Battery Materials: Progress, Challenges, and Future Perspectives

Advanced Functional Materials, EarlyView.
AI is transforming the research paradigm of battery materials and reshaping the entire landscape of battery technology. This comprehensive review summarizes the cutting‐edge applications of AI in the advancement of battery materials, underscores the critical challenges faced in harnessing the full potential of AI, and proposes strategic guidance for ...
Qingyun Hu, Junyuan Lu, Jian Hui, Ziyuan Rao, Yang Ren, Hong Wang   +5 more
wiley   +1 more source

Innate immune response to AAV-based gene therapy vectors: Mechanisms of complement activation and cytokine release. [PDF]

Mol Ther Methods Clin Dev
Xicluna R, Schwalie PC, Bell E, Von Tell D, Steiner G, Seeger E, Freen-van Heeren JJ, Turksma AW, Pouw RB, Schwandt T, Otteneder MB, Rispens T, Brouwer MC, Bertinetti-Lapatki C, Haegel H.   +14 more
europepmc   +1 more source