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Effects of anesthesia and operation on the classical pathway of complement activation
Clinical Immunology and Immunopathology, 1982Abstract The present study examined whether anesthesia and operation could alter serum complement function as reflected by CH 50 levels and individual component activity. Classical complement pathway function was significantly reduced, as reflected by lowered CH 50 levels, in patients undergoing anesthesia and operation.
Robert E. Lewis +2 more
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Synthesis of classical pathway complement components by chondrocytes.
Immunology, 1996Using immunohistochemical studies, C1q, C1s, C4 and C2 were detected in chondrocytes in normal human articular cartilage and macroscopically normal articular cartilage from the inferior surfaces of hip joints of patients with osteoarthritis. Using reverse-transcribed polymerase chain reaction (RT-PCR), mRNA for C1q, C1s, C4 and C2 was also detected in ...
Bradley, K. +6 more
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[22] Molecular titration of components of the classical complement pathway
1983Publisher Summary The complement system consists of at least 20 serum proteins that interact in a precisely defined sequence resulting in the production of biologically active by-products and, ultimately, in the destruction of, or damage to, a suitably sensitized cell. Activation of this system can be achieved by two mechanisms, namely, the classical
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CLASSICAL COMPLEMENT PATHWAY IN HIV INFECTION
The Lancet, 1989E T Davies +5 more
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Classical and alternative pathway of complement in amphibia
Developmental & Comparative Immunology, 1983B. Hofmanová +3 more
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The Intrinsic Coagulation/Kinin Pathway- The Classical Complement Pathway and their Interactions
1986Berhane Ghebrehiwet +2 more
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