Results 201 to 210 of about 23,299 (223)
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Deposition of mannose‐binding lectin and ficolins and activation of the lectin pathway of complement on the surface of polyurethane tubing used for cardiopulmonary bypass

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2017
AbstractThe artificial surface used for cardiopulmonary bypass (CPB) is a crucial factor activating the complement system and thus contributing to the generation of a systemic inflammatory response. The activation of classical and alternative pathways on this artificial surface is well known.
Łukasz, Eppa   +5 more
openaire   +2 more sources

Emerging role of the mannose-binding lectin-dependent pathway of complement activation in clinical organ transplantation

Current Opinion in Organ Transplantation, 2011
Over the past decade, the role of the complement system in solid organ transplantation has received increased attention. A number of experimental and epidemiological studies have suggested that the lectin pathway plays a role in infectious complications, rejection and long-term outcome after transplantation.
Berger, S.P., Daha, M.R.
openaire   +3 more sources

A novel measurement method for activation of the lectin complement pathway via both mannose-binding lectin (MBL) and L-ficolin

Journal of Immunological Methods, 2009
Mannose-binding lectin (MBL), L-ficolin and H-ficolin are human serum lectins, all of which form complexes with MBL-associated serine proteases (MASP). The lectin-MASP complexes bind to the surface of microbes, leading to activation of the lectin pathway of complement.
Hiroyuki, Inoshita   +11 more
openaire   +2 more sources

Analysis of the classical, alternative, and mannose binding lectin pathway of the complement system in the pathogenesis of oligoarticular juvenile idiopathic arthritis

Rheumatology International, 2011
The complement system plays a role in the pathogenesis of some autoimmunopathies. This longitudinal study evaluates the contribution of the complement system in the pathogenesis of oligoarticular juvenile idiopathic arthritis (JIA). Serum of the peripheral blood and the synovial fluid were investigated for the activity of the classical (CP), the ...
Juergen, Brunner   +6 more
openaire   +2 more sources

Mannose-binding lectin as part of the complement pathway: characterization in non-inflamed and inflamed human eyes.

Clinical & experimental ophthalmology, 2012
Mannose-binding lectin plays a central effector role in the lectin pathway of complement activation. Frequently occurring MBL2 polymorphisms result in mannose-binding lectin deficiency, which increases susceptibility to infection. We characterized mannose-binding lectin levels and function in non-inflamed and inflamed human eyes, and evaluated its ...
Chow, Sing-Pey   +4 more
openaire   +2 more sources

Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis

Clinical and Experimental Immunology, 2005
T E Mollnes   +2 more
exaly  

Secondary Cell Wall Polymers of Enterococcus faecalis Are Critical for Resistance to Complement Activation via Mannose-binding Lectin

Journal of Biological Chemistry, 2012
Suzan H M Rooijakkers   +2 more
exaly  

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