Results 31 to 40 of about 1,176 (261)
Complement Regulatory Proteins [PDF]
Journal of the American Society of Nephrology, 2003 In this issue of JASN , Turnberg et al. ([1][1]) report that the manifestations of disease in an immune complex-mediated glomerulonephritis model are exacerbated in Cd59a knockout mice. Exacerbation was associated with an increase in C9 deposition in glomeruli, suggesting that the deficiency ...
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Journal of Translational Medicine, 2020 Background Complement Regulatory Proteins (CRPs), especially CD55 primarily negate complement factor 3-mediated injuries and maintain tissue homeostasis during complement cascade activation.
Mohammad Afzal Khan +6 more
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mBio, 2022 Entamoeba histolytica is the cause of amoebiasis. The trophozoite (amoeba) form of this parasite is capable of invading the intestine and can disseminate through the bloodstream to other organs.
Hannah W. Miller +2 more
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Frontiers in Immunology, 2021 Chagas’ disease is a zoonotic parasitic ailment now affecting more than 6 million people, mainly in Latin America. Its agent, the protozoan Trypanosoma cruzi, is primarily transmitted by endemic hematophagous triatomine insects.
Galia Ramírez-Toloza +5 more
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Mutations in complement regulatory proteins predispose to preeclampsia: a genetic analysis of the PROMISSE cohort. [PDF]
PLoS Medicine, 2011 Pregnancy in women with systemic lupus erythematosus (SLE) or antiphospholipid antibodies (APL Ab)--autoimmune conditions characterized by complement-mediated injury--is associated with increased risk of preeclampsia and miscarriage. Our previous studies
Jane E Salmon +9 more
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Complement regulatory proteins and autoimmunity
Autoimmunity, 2006 The complement system is known to be involved in autoimmunity at several levels. Activated complement contributes to the inflammatory tissue injury characteristic of many autoimmune disease settings. On the other hand, early components of the classical pathway, including C1q, C4 and C2, are thought to be important for disposing apoptotic cellular ...
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Antibodies against complement-regulatory proteins on platelets in immune thrombocytopenia
Platelets, 2017 In immune thrombocytopenia (ITP), antibodies reacting with platelet membrane glycoproteins (GP) mediate premature platelet cleavage, resulting in thrombocytopenia and therefore a risk of bleeding.
Ursula Unterberger +3 more
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Primary extranodal diffuse large B‐cell lymphoma: Molecular features, treatment, and prognosis
Aging and Cancer, Volume 3, Issue 3-4, Page 133-146, September-December 2022., 2022 One‐third of DLBCL arises from extranodal organs and is challenging to manage. Molecular features are critical to elucidate the differences in clinical features, predict the disease prognosis, and improve effective targeted therapeutic strategies. Abstract Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of non‐Hodgkin's lymphoma and ...
Si‐Yuan Chen +3 more
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The Complement System: A Prey of Trypanosoma cruzi
Frontiers in Microbiology, 2017 Trypanosoma cruzi is a protozoan parasite known to cause Chagas disease (CD), a neglected sickness that affects around 6–8 million people worldwide. Originally, CD was mainly found in Latin America but more recently, it has been spread to countries in ...
Kárita C. F. Lidani +3 more
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CD59 (CD59 molecule, complement regulatory protein) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Review on CD59 (CD59 molecule, complement regulatory protein), with data on DNA, on the protein encoded, and where the gene is implicated.
Donev, RM, Kolev, MV
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