Results 21 to 30 of about 305,759 (329)

CD59 (CD59 molecule, complement regulatory protein) [PDF]

open access: greenAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2013
Review on CD59 (CD59 molecule, complement regulatory protein), with data on DNA, on the protein encoded, and where the gene is implicated.
RM Donev, MV Kolev
openalex   +4 more sources

Expression of the membrane complement regulatory proteins (CD55 and CD59) in human thymus.

open access: greenFolia Histochemica et Cytobiologica, 2007
CD59 is one of the key molecules involved in cell protection against autologus complement. The fact that complement regulatory proteins are able to prevent hyperacute rejection of organs in pig to primate model, raises the question of possible complement
Agnieszka Kinsner   +6 more
doaj   +3 more sources

Protection of Baculovirus Vectors Expressing Complement Regulatory Proteins against Serum Complement Attack

open access: diamondBiological and Pharmaceutical Bulletin, 2018
Baculovirus vectors (BVs) enable safe and efficient gene delivery to mammalian cells and are useful in a wide range of applications, including gene therapy and in vivo analysis of gene functions. We previously developed BVs expressing malaria sporozoite surface proteins for targeting liver cells or hepatocytes.
Yusuke K. Kawai   +3 more
openalex   +4 more sources

Chandipura virus evades human complement by recruiting host complement regulatory proteins

open access: yesInternational Journal of Infectious Diseases, 2020
U. Kunnakkadan, J. Bernet Johnson
doaj   +2 more sources

Upregulation of complement proteins in lung cancer cells mediates tumor progression

open access: yesFrontiers in Oncology, 2023
IntroductionIn vivo, cancer cells respond to signals from the tumor microenvironment resulting in changes in expression of proteins that promote tumor progression and suppress anti-tumor immunity.
Emily K. Kleczko   +16 more
doaj   +1 more source

The Defensive Interactions of Prominent Infectious Protozoan Parasites: The Host’s Complement System

open access: yesBiomolecules, 2022
The complement system exerts crucial functions both in innate immune responses and adaptive humoral immunity. This pivotal system plays a major role dealing with pathogen invasions including protozoan parasites.
Sajad Rashidi   +5 more
doaj   +1 more source

Genetic engineering strategies to prevent the effects of antibody and complement on xenogeneic chondrocytes [PDF]

open access: yesEuropean Cells & Materials, 2015
Advances in animal transgenesis may allow using xenogeneic chondrocytes in tissue-engineering applications for clinical cartilage repair. Porcine cartilage is rejected by humoral and cellular mechanisms that could be overcome by identifying key molecules
R Sommaggio   +5 more
doaj   +1 more source

Mathematical Modeling of Complement Pathway Dynamics for Target Validation and Selection of Drug Modalities for Complement Therapies

open access: yesFrontiers in Pharmacology, 2022
Motivation: The complement pathway plays a critical role in innate immune defense against infections. Dysregulation between activation and regulation of the complement pathway is widely known to contribute to several diseases.
Loveleena Bansal   +8 more
doaj   +1 more source

Virus-Encoded Complement Regulators: Current Status

open access: yesViruses, 2021
Viruses require a host for replication and survival and hence are subjected to host immunological pressures. The complement system, a crucial first response of the host immune system, is effective in targeting viruses and virus-infected cells, and ...
Anwesha Sinha   +4 more
doaj   +1 more source

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