Results 141 to 150 of about 24,757,633 (403)

Steiner systems and configurations of points [PDF]

open access: yesarXiv, 2020
The aim of this paper is to make a connection between design theory and algebraic geometry/commutative algebra. In particular, given any Steiner System $S(t,n,v)$ we associate two ideals, in a suitable polynomial ring, defining a Steiner configuration of points and its Complement.
arxiv  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

A nested Schur complement solver with mesh-independent convergence for the time domain photonics modeling [PDF]

open access: yesarXiv, 2019
A nested Schur complement solver is proposed for iterative solution of linear systems arising in exponential and implicit time integration of the Maxwell equations with perfectly matched layer (PML) nonreflecting boundary conditions. These linear systems are the so-called double saddle point systems whose structure is handled by the Schur complement ...
arxiv  

Role of the Complement System in the Response to Orthopedic Biomaterials

open access: yesInternational Journal of Molecular Sciences, 2018
Various synthetic biomaterials are used to replace lost or damaged bone tissue that, more or less successfully, osseointegrate into the bone environment.
Yvonne Mödinger   +3 more
semanticscholar   +1 more source

Preferred Measurements: Optimality and Stability in Quantum Parameter Estimation

open access: yes, 2009
We explore precision in a measurement process incorporating pure probe states, unitary dynamics and complete measurements via a simple formalism. The concept of `information complement' is introduced.
Barndorff-Nielsen O E   +6 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Arrangements and local systems

open access: yes, 1999
We use stratified Morse theory to construct a complex to compute the cohomology of the complement of a hyperplane arrangement with coefficients in a complex rank one local system. The linearization of this complex is shown to be the Orlik-Solomon algebra
Cohen, Daniel C., Orlik, Peter
core   +1 more source

Preconditioning of a hybridized discontinuous Galerkin finite element method for the Stokes equations

open access: yes, 2018
We present optimal preconditioners for a recently introduced hybridized discontinuous Galerkin finite element discretization of the Stokes equations.
Rhebergen, Sander, Wells, Garth N.
core   +1 more source

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