Results 231 to 240 of about 19,068,086 (301)

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

The interaction of fibrinolysis and the complement system in patients with acute pulmonary embolism, treated with ultrasound-assisted catheter-directed thrombolysis. [PDF]

Thromb J
Draxler DF, Barrett CD, Brodard J, Maginot ER, Chalkou K, Ho H, Keragala CB, Heg D, Kremer Hovinga JA, Moore EE, Medcalf RL, Angelillo-Scherrer A, Stortecky S.   +12 more
europepmc   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice. [PDF]

Nat Commun
Zhang Y, Watson B, Rattan A, Lee T, Chawla S, Geistlinger L, Guan Y, Lord FB, Ma M, Miwa T, Golla M, Caldarone BJ, Song WC, Moffitt JR, Carroll MC.   +14 more
europepmc   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

The complement system and kidney cancer: pathogenesis to clinical applications. [PDF]

J Clin Invest
Aalinkeel R, Quigg RJ, Alexander J.
europepmc   +1 more source

Spatial and Volumetric Characteristics of Glioblastoma: Associations With Clinical Presentation and Survival

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou, Marc Jaskir, Julian Gal, Yombe Fonkeu, Christos Davatzikos, MacLean P. Nasrallah, Jose Garcia, Rubo Xing, Stephen J. Bagley, Arati Desai, Richard E. Phillips, Steven Tobochnik, Colin A. Ellis, James J. Gugger, Nishant Sinha, Joel M. Stein, Kathryn A. Davis   +16 more
wiley   +1 more source

Genetic mapping of complement system proteins for islet autoimmunity in children with high risk of T1D. [PDF]

Commun Biol
Hu X, Webb-Robertson BM, Parikh HM, Nakayasu ES, Onengut-Gumuscu S, Chen WM, Frazer-Abel A, Metz TO, Rich SS, Rewers MJ, Manichaikul A.   +10 more
europepmc   +1 more source

Emerging role of complement system in the induction of neuroinflammation in adenylosuccinate lyase deficiency disorder. [PDF]

Brain Behav Immun Health
Magnusen AF, Hopkin RJ, Vorhees C, Wilson E, Moehlman M, Hallinan B, Erickson C, DelBello MP, Marsili L, Coufal NG, Pandey MK.   +10 more
europepmc   +1 more source

Targeting the complement system: notes on therapeutic strategies for renal cancer. [PDF]

Future Med Chem
Lasorsa F, Rutigliano M, Milella M, Ditonno P, Lucarelli G.   +4 more
europepmc   +1 more source