ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu +10 more
wiley +1 more source
Isolation and characterization of factor I of the bovine complement system [PDF]
Marilyn Menger, W.P. Aston
openalex +1 more source
Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer +3 more
wiley +1 more source
Gut complement system: a new frontier in microbiota-host communication and intestinal homeostasis. [PDF]
Tian X +7 more
europepmc +1 more source
The complement system contributes to the immunosuppressive microenvironment of uveal melanoma
I. Zherka +4 more
openalex +1 more source
#2000 Analysis between site-specific N-glycosylation of monoclonal immunoglobulin and complement system activation [PDF]
Wanhong Lu, Huixian LI, Xinfang Xie
openalex +1 more source
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai +13 more
wiley +1 more source
Impact of complement system proteins on the clinical progression of hospitalized patients with COVID-19. [PDF]
de Andrade LV +5 more
europepmc +1 more source
Meningovascular Inflammation in Cerebral Amyloid Angiopathy‐Related Cortical Superficial Siderosis
ABSTRACT The role of inflammation in cortical superficial siderosis (cSS), a marker of cerebral amyloid angiopathy (CAA) linked to high hemorrhage risk, is unclear. We examined 15 patients with cSS using 3 T post‐contrast vessel wall MRI (VWI) and CSF analysis.
Philipp Arndt +8 more
wiley +1 more source
A spatial atlas of the complement system uncovers unique expression patterns in postnatal brain development in mice. [PDF]
Zhang Y +14 more
europepmc +1 more source

