Results 41 to 50 of about 1,195,438 (288)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2021 The last 15 years have seen an explosion of new findings on the role of complement, a major arm of the immune system, in the central nervous system (CNS) compartment including contributions to cell migration, elimination of synapse during development ...
B. Paul Morgan +2 more
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
The Complement System in the Central Nervous System: From Neurodevelopment to Neurodegeneration
Biomolecules, 2022 The functions of the complement system to both innate and adaptive immunity through opsonization, cell lysis, and inflammatory activities are well known.
Ying Chen +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Complement in Sickle Cell Disease: Are We Ready for Prime Time?
Journal of Blood Medicine, 2021 Christos Varelas,1 Athina Tampaki,2 Ioanna Sakellari,1 &Agr;chilles Anagnostopoulos,1 Eleni Gavriilaki,1,* Efthymia Vlachaki2,* 1Hematology Department – BMT Unit, G.
Varelas C +5 more
doaj
Streptococcus pneumoniae interactions with the complement system
Frontiers in Cellular and Infection Microbiology, 2022 Host innate and adaptive immunity to infection with Streptococcus pneumoniae is critically dependent on the complement system, demonstrated by the high incidence of invasive S.
Eliza Gil +2 more
doaj +1 more source
Oka properties of complements of holomorphically convex sets [PDF]
arXiv, 2020 Our main theorem states that the complement of a compact holomorphically convex set in a Stein manifold with the density property is an Oka manifold. This gives a positive answer to the well-known long-standing problem in Oka theory whether the complement of a compact polynomially convex set in $\mathbb{C}^{n}$ $(n>1)$ is Oka.
arxiv
Cohomology of $\mathbb{Z}$-local systems on complex hyperplane arrangement complements [PDF]
arXiv, 2022 We prove a Cohen-Dimca-Orlik type theorem for rank one $\mathbb{Z}$-local systems on complex hyperplane arrangement complements. This settles a recent conjecture of S. Sugawara.
arxiv