Results 31 to 40 of about 1,857,462 (287)
The tumour microenvironment links complement system dysregulation and hypoxic signalling. [PDF]
The complement system is an innate immune pathway typically thought of as part of the first line of defence against "non-self" species. In the context of cancer, complement has been described to have an active role in facilitating cancer-associated ...
Giaccia, Amato J +4 more
core +1 more source
The Complement System and Preeclampsia [PDF]
Current Hypertension Reports, 2017 Preeclampsia affects 3-4% of pregnancies with few treatment options to reduce maternal and fetal harm. Recent evidence that targeting the complement system may be an effective therapeutic strategy in prevention or treatment of preeclampsia will be reviewed.Studies in humans confirm the safety and efficacy of C5 blockade in complement-mediated disorders
Jean F, Regal +2 more
openaire +2 more sources
Complement activation and protein adsorption by carbon nanotubes [PDF]
As a first step to validate the use of carbon nanotubes as novel vaccine or drug delivery devices, their interaction with a part of the human immune system, complement, has been explored.
Flahaut, Emmanuel +5 more
core +1 more source
Modeling Commodity Flow as a Statistical Function of Lock Unavailability and Usage [PDF]
The inland waterway system in the United States allows for the transportation of commodities, and interruptions to the system can have remarkable economic consequences.
McGee, Grace
core +2 more sources
Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host
Frontiers in Microbiology, 2019 Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
doaj +1 more source
Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. [PDF]
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and cancer. While p53 activation is responsible for many features of DBA, the role of immune system is less defined.
Bibikova, Elena +5 more
core +1 more source
Frontiers in Immunology, 2020 Preeclampsia is one of the leading causes of maternal and neonatal mortality and morbidity worldwide, affecting 2–8% of all pregnancies. Studies suggest a link between complement activation and preeclampsia.
E. Pierik +6 more
doaj +1 more source
Frontiers in Cellular Neuroscience, 2021 As part of the innate immune system, complement plays a critical role in the elimination of pathogens and mobilization of cellular immune responses. In the central nervous system (CNS), many complement proteins are locally produced and regulate nervous ...
Noriko Shinjyo +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Detection and characterisation of Complement protein activity in bovine milk by bactericidal sequestration assay [PDF]
Susan Maye is in receipt of a Teagasc Walsh Fellowship. Financial support by the Department of Agriculture, Food and the Marine is gratefully acknowledged.Copyright © Proprietors of Journal of Dairy Research 2015 (Institute of Food Research and the ...
Fitzgerald, Gerald F +3 more
core +1 more source