Results 21 to 30 of about 1,847,156 (328)
Complement System: An Immunotherapy Target in Colorectal Cancer
Frontiers in Immunology, 2022 Colorectal cancer (CRC) is the third most common malignant tumor and the second most fatal cancer worldwide. Several parts of the immune system contribute to fighting cancer including the innate complement system.
Iman M. Talaat +7 more
doaj +1 more source
Two-Color Terawatt Laser System For High-Intensity Laser-Plasma Experiments [PDF]
, 2012 We report a two-color terawatt laser system for use in controlling laser-plasma instabilities. The system includes a commercial 45 TW Ti:Sapphire laser system at 800 nm, temporally synchronized with a 1 TW CPA Raman-Ti:Sapphire hybrid laser centered at ...
Downer, M. C. +2 more
core +1 more source
Francisella tularensis Confronts the Complement System
Frontiers in Cellular and Infection Microbiology, 2017 Francisella tularensis has developed a number of effective evasion strategies to counteract host immune defenses, not the least of which is its ability to interact with the complement system to its own advantage.
Susan R. Brock, Michael J. Parmely
doaj +1 more source
New insights into the immune functions of podocytes: the role of complement
Molecular and Cellular Pediatrics, 2023 Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In addition to their adhesive properties in maintaining the integrity of the filtration barrier, they have ...
Valentina Bruno +3 more
doaj +1 more source
COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +4 more
core +1 more source
British Journal of Anaesthesia, 1979 The existence of the complement system was first recognized at the end of the 19th century by the ability of serum to enhance the destruction of bacteria and the requirement of a heat-labile serum factor necessary for the lysis of red cells. Since then extensive research by many groups of workers led to a detailed understanding of the structure ...
openaire +3 more sources
Combined anti-C1-INH and radiotherapy against glioblastoma
BMC Cancer, 2023 Background A more effective immune response against glioblastoma is needed in order to achieve better tumor control. Radiotherapy can induce anti-tumor mediated immune reactions, in addition to its dose response effects.
Emma Liljedahl +7 more
doaj +1 more source
Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]
, 2016 Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J. +7 more
core +1 more source
Acidosis activates complement system in vitro
Mediators of Inflammation, 1998 We investigated the in vitro effect of different form s of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 μ mol/ml blood) or lactic acid (5.5 μ mol/ml) to heparin blood (N=12)
Michael Emeis +5 more
doaj +1 more source
Frontiers in Immunology, 2018 The complement system has moved into the focus of drug development efforts in the last decade, since its inappropriate or uncontrolled activation has been recognized in many diseases.
József Dobó +2 more
doaj +1 more source