Results 51 to 60 of about 24,198,541 (380)

Acidosis activates complement system in vitro

open access: yesMediators of Inflammation, 1998
We investigated the in vitro effect of different form s of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 μ mol/ml blood) or lactic acid (5.5 μ mol/ml) to heparin blood (N=12)
Michael Emeis   +5 more
doaj   +1 more source

New insights into the immune functions of podocytes: the role of complement

open access: yesMolecular and Cellular Pediatrics, 2023
Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In addition to their adhesive properties in maintaining the integrity of the filtration barrier, they have ...
Valentina Bruno   +3 more
doaj   +1 more source

Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance [PDF]

open access: yesIranian Journal of Immunology, 2023
Two central questions in COVID-19 treatment which should be considered are: “How does the imbalance of the complement system affect the therapeutic approaches?” and “Do we consider complement inhibitors in therapeutic protocols?”.
Mehdi Torabizadeh   +5 more
doaj   +1 more source

Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]

open access: yes, 2015
Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K.   +10 more
core   +1 more source

Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host

open access: yesFrontiers in Microbiology, 2019
Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao   +4 more
doaj   +1 more source

Complement System: Promoter or Suppressor of Cancer Progression?

open access: yesAntibodies, 2020
Constituent of innate immunity, complement is present in the tumor microenvironment. The functions of complement include clearance of pathogens and maintenance of homeostasis, and as such could contribute to an anti-tumoral role in the context of certain
M. Revel   +4 more
semanticscholar   +1 more source

Two-Color Terawatt Laser System For High-Intensity Laser-Plasma Experiments [PDF]

open access: yes, 2012
We report a two-color terawatt laser system for use in controlling laser-plasma instabilities. The system includes a commercial 45 TW Ti:Sapphire laser system at 800 nm, temporally synchronized with a 1 TW CPA Raman-Ti:Sapphire hybrid laser centered at ...
Downer, M. C.   +2 more
core   +1 more source

Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19

open access: yesJournal of Thrombosis and Thrombolysis, 2020
Coronavirus disease-2019 (COVID-19) is a rapidly evolving health crisis caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Xin Wang, K. Sahu, J. Černý
semanticscholar   +1 more source

Exploring a rheonomic system [PDF]

open access: yes, 1999
A simple and illustrative rheonomic system is explored in the Lagrangian formalism. The difference between Jacobi's integral and energy is highlighted. A sharp contrast with remarks found in the literature is pointed out.
Antonio S de Castro   +6 more
core   +2 more sources

Preferential association of hepatitis C virus with CD19+ B cells is mediated by complement system [PDF]

open access: yes, 2016
Extrahepatic disease manifestations are common in chronic hepatitis C virus (HCV) infection. The mechanism of HCV-related lymphoproliferative disorders is not fully understood.
Alter, Harvey J.   +7 more
core   +1 more source

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