Results 51 to 60 of about 24,757,633 (403)
Acidosis activates complement system in vitro
Mediators of Inflammation, 1998 We investigated the in vitro effect of different form s of acidosis (pH 7.0) on the formation of anaphylatoxins C3a and C5a. Metabolic acidosis due to addition of hydrochloric acid (10 μ mol/ml blood) or lactic acid (5.5 μ mol/ml) to heparin blood (N=12)
Michael Emeis +5 more
doaj +1 more source
New insights into the immune functions of podocytes: the role of complement
Molecular and Cellular Pediatrics, 2023 Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In addition to their adhesive properties in maintaining the integrity of the filtration barrier, they have ...
Valentina Bruno +3 more
doaj +1 more source
COMPLEMENT-MEDIATED ADIPOCYTE LYSIS BY NEPHRITIC FACTOR SERA [PDF]
, 1993 Recent data indicate a previously unsuspected link between the complement system and adipocyte biology. Murine adipocytes produce key components of the alternative pathway of complement and are able to activate this pathway.
Lachmann, PJ +4 more
core +1 more source
Implications of Complement Imbalance in COVID-19: A Molecular Mechanistic Discussion on the Importance of Complement Balance [PDF]
Iranian Journal of Immunology, 2023 Two central questions in COVID-19 treatment which should be considered are: “How does the imbalance of the complement system affect the therapeutic approaches?” and “Do we consider complement inhibitors in therapeutic protocols?”.
Mehdi Torabizadeh +5 more
doaj +1 more source
Mast cells and complement system: Ancient interactions between components of innate immunity
Allergy. European Journal of Allergy and Clinical Immunology, 2020 The emergence and evolution of the complement system and mast cells (MCs) can be traced back to sea urchins and the ascidian Styela plicata, respectively. Acting as a cascade of enzymatic reactions, complement is activated through the classical (CP), the
Daniel Elieh-Ali-Komi +3 more
semanticscholar +1 more source
Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host
Frontiers in Microbiology, 2019 Parasitic infections induce host immune responses that eliminate the invading parasites. However, parasites have evolved to develop many strategies to evade host immune attacks and survive in a hostile environment. The complement system acts as the first
Shuai Shao +4 more
doaj +1 more source
Journal of Thrombosis and Thrombolysis, 2020 Coronavirus disease-2019 (COVID-19) is a rapidly evolving health crisis caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Xin Wang, K. Sahu, J. Černý
semanticscholar +1 more source
Two-Color Terawatt Laser System For High-Intensity Laser-Plasma Experiments [PDF]
, 2012 We report a two-color terawatt laser system for use in controlling laser-plasma instabilities. The system includes a commercial 45 TW Ti:Sapphire laser system at 800 nm, temporally synchronized with a 1 TW CPA Raman-Ti:Sapphire hybrid laser centered at ...
Downer, M. C. +2 more
core +1 more source
Complement System: Promoter or Suppressor of Cancer Progression?
Antibodies, 2020 Constituent of innate immunity, complement is present in the tumor microenvironment. The functions of complement include clearance of pathogens and maintenance of homeostasis, and as such could contribute to an anti-tumoral role in the context of certain
Margot Revel +4 more
semanticscholar +1 more source
Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. [PDF]
, 2017 Neuromyelitis optica spectrum disorders (herein called NMO) is an inflammatory demyelinating disease of the central nervous system in which pathogenesis involves complement-dependent cytotoxicity (CDC) produced by immunoglobulin G autoantibodies ...
Verkman, Alan S, Yao, Xiaoming
core +2 more sources