Results 271 to 280 of about 2,103,871 (307)

Proteomic profiling of the serum of patients with COVID-19 reveals key factors in the path to clinical improvement. [PDF]

open access: yesClin Transl Med
Seong H   +11 more
europepmc   +1 more source

Molecular Mechanisms of Complement System Proteins and Matrix Metalloproteinases in the Pathogenesis of Age-Related Macular Degeneration.

Current molecular medicine, 2019
Age related macular degeneration (AMD) is an eye disorder affecting predominantly the older people above the age of 50 years in which the macular region of retina deteriorates, resulting in the loss of central vision. The key features associated with the
N. Mansoor   +6 more
semanticscholar   +1 more source

The complement system

Oxford Textbook of Medicine, 2020
The complement system, consisting of soluble and membrane-bound proteins, is a major effector mechanism of host defence against infection and inflammatory responses.
M. Botto, Matthew C Pickering
semanticscholar   +1 more source

Complement system in lung transplantation

Clinical Transplantation, 2018
The complement system is a cascade of multiple proteins that have been known to mediate inflammatory response. This tightly regulated system has been recognized to play a role in adaptive immunity via humoral and cell‐mediated processes.
H. Ali   +4 more
semanticscholar   +1 more source

Terminal complexes of the complement system: new structural insights and their relevance to function

Immunological Reviews, 2016
Complement is a key component of innate immunity in health and a powerful driver of inflammation and tissue injury in disease. The biological and pathological effects of complement activation are mediated by activation products. These come in two flavors:
B. Morgan   +3 more
semanticscholar   +1 more source

Sites of Production of Primate Serum Proteins Associated with the Complement System.∗

Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine, 1967
Summary Various human and monkey tissues, including liver, spleen, bone marrow, and lung were found to incorporate C14-amino acids into 11S globulin (C′1q) in vitro.
V. Stecher, J. Morse, G. Thorbecke
semanticscholar   +1 more source

Synovial fibroblast-like cells synthesize seven proteins of the complement system.

Arthritis & Rheumatism, 1988
Fibroblast-like cells from synovial tissue obtained during arthroscopy in 4 young adults with recent knee trauma were biosynthetically labeled with 35S-methionine, and protein production was quantitated by immunoprecipitation and sodium dodecyl sulfate ...
Y. Katz, R. Strunk
semanticscholar   +1 more source

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