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[Complementarity-determining region 3 analysis of T cell receptor beta chain variable region in peripheral blood mononuclear cells cultured with interleukin-2].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010
To analyze the drift of the complementarity-determining region 3 (CDR3) of T cell receptor beta (TCRbeta) chain variable region in T cells of healthy volunteers cultured with interleukin-2 (IL-2).T cells were isolated from the peripheral blood and cultured in vitro in the presence of IL-2.
Hong, Chang   +7 more
openaire   +1 more source

Contribution of Complementarity-Determining Region 3 of the T-Cell Receptor Vδ2 Chain to the Recognition of Aminobisphosphonates by Human γδ T-Cells.

International journal of hematology, 2004
Human gammadelta T-lymphocytes expressing Vgamma2Vdelta2 T-cell receptors (TCRs) can be stimulated by aminobisphosphonates and can kill certain tumor cells. Although germline-encoded lysine residues on the Jgamma1.2 segment have been demonstrated to be essential for the recognition of nonpeptide antigens by human gammadelta T-cells, the role of the ...
Hayato, Nishimura   +5 more
openaire   +1 more source

Downsizing antibodies: Towards complementarity-determining region (CDR)-based peptide mimetics

Bioorganic Chemistry, 2022
Kevin Van Holsbeeck   +2 more
exaly  

Conformational Dynamics of Complementarity-determining Region H3 of an Anti-dansyl Fv Fragment in the Presence of its Hapten

Journal of Molecular Biology, 2005
Masayoshi Nakasako   +2 more
exaly  

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