Results 131 to 140 of about 11,073 (199)

High-yield Escherichia coli -based cell-free expression of human proteins [PDF]

, 2018
Production of sufficient amounts of human proteins is a frequent bottleneck in structural biology. Here we describe an Escherichia coli-based cell-free system which yields mg-quantities of human proteins in N-terminal fusion constructs with the GB1 ...
Michel, Erich, Wüthrich, Kurt
core  

Compound porcine cerebroside and ganglioside injection attenuates cerebral ischemia–reperfusion injury in rats by targeting multiple cellular processes

Neuropsychiatric Disease and Treatment, 2017
Mingyang Wang,* Yi Zhang,* Lu Feng, Ji Zheng, Shujie Fan, Junya Liu, Nan Yang, Yanyong Liu, Pingping Zuo Department of Pharmacology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing ...
Wang M, Zhang Y, Feng L, Zheng J, Fan S, Liu J, Yang N, Liu Y, Zuo P   +8 more
doaj  

Software engineering and Ada (Trademark) training: An implementation model for NASA [PDF]

The choice of Ada for software engineering for projects such as the Space Station has resulted in government and industrial groups considering training programs that help workers become familiar with both a software culture and the intricacies of a new ...
Freedman, Glenn, Legrand, Sue
core   +1 more source

Clamping complexin [PDF]

Nature Reviews Molecular Cell Biology, 2009
openaire   +1 more source

NOX Inhibitors - A Promising Avenue for Ischemic Stroke. [PDF]

, 2017
NADPH-oxidase (NOX) mediated superoxide originally found on leukocytes, but now recognized in several types of cells in the brain. It has been shown to play an important role in the progression of stroke and related cerebrovascular disease.
Kim, Jong Youl, Lee, Jong Eun, Park, Joohyun, Yenari, Midori A   +3 more
core   +1 more source

GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis

Communications Biology
Essential tremor (ET) is a prevalent neurological disorder with a largely unknown underlying biology. In this genome-wide association study meta-analysis, comprising 16,480 ET cases and 1,936,173 controls from seven datasets, we identify 12 sequence ...
Astros Th. Skuladottir, Lilja Stefansdottir, Gisli H. Halldorsson, Olafur A. Stefansson, Anna Bjornsdottir, Palmi Jonsson, Vala Palmadottir, Thorgeir E. Thorgeirsson, G. Bragi Walters, Rosa S. Gisladottir, Gyda Bjornsdottir, Gudrun A. Jonsdottir, Patrick Sulem, Daniel F. Gudbjartsson, Kirk U. Knowlton, David A. Jones, Aigar Ottas, Estonian Biobank, Ole B. Pedersen, Maria Didriksen, Søren Brunak, Karina Banasik, Thomas Folkmann Hansen, Christian Erikstrup, DBDS Genomic Consortium, Jan Haavik, Ole A. Andreassen, David Rye, Jannicke Igland, Sisse Rye Ostrowski, Lili A. Milani, Lincoln D. Nadauld, Hreinn Stefansson, Kari Stefansson   +33 more
doaj   +1 more source

Synaptophysin chaperones the assembly of 12 SNAREpins under each ready-release vesicle. [PDF]

Proc Natl Acad Sci U S A, 2023
Bera M, Radhakrishnan A, Coleman J, K Sundaram RV, Ramakrishnan S, Pincet F, Rothman JE.   +6 more
europepmc   +1 more source

Proper toric maps over finite fields [PDF]

, 2015
De Cataldo, M.
core   +2 more sources

Complexin cross-links pre-fusion SNAREs into a zig-zag array: a structure-based model for complexin clamping

, 2011
Complexin prevents SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. To understand the mechanism for this inhibition, we determined the structure of complexin bound to a mimetic of a pre-fusion SNAREpin lacking the portion of the v-SNARE which zippers last to trigger fusion.
Kümmel, Daniel, Krishnakumar, Shyam S., Radoff, Daniel T., Li, Feng, Giraudo, Claudio G., Pincet, Frederic, Rothman, James E., Reinisch, Karin M.   +7 more
openaire   +1 more source

Endocytic protein AP180 assembly domain regulates synaptic vesicle size and release in Caenorhabditis elegans. [PDF]

PLoS Biol
Wang Y, Wu L, Zhang L, Dong Y, Pant A, Liu Y, Bai J.   +6 more
europepmc   +1 more source