Results 151 to 160 of about 2,250,906 (262)

Advancing <i>Mytilus galloprovincialis</i> Primary Cell Cultures as Models for Bioactive Compound Screening and Environmental Safety Assessment. [PDF]

Biology (Basel)
Ma Y, De Marchi L, Monni G, Giannessi J, Meucci V, Lenzi A, Vasarri M, Degl'Innocenti D, Pretti C.   +8 more
europepmc   +1 more source

A context-aware deconfounding autoencoder for robust prediction of personalized clinical drug response from cell-line compound screening. [PDF]

Nat Mach Intell, 2022
He D, Liu Q, Wu Y, Xie L.
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Highly sensitive genotyping of MTHFR C677T polymorphisms using a novel RPA-LDR-qPCR assay

Acta Biochimica et Biophysica Sinica, 2022
Si Xinxin, Gu Qinghua, Zhao Chenjie, Zhang Xiao, Xiao Tingting, Li Yu, Ying Wei, Gao Song   +7 more
doaj   +1 more source

A dermis-on-a-chip model for compound screening. [PDF]

Mater Today Bio
Abdo D, Zhao Y, Okhovatian S, Jiménez Vargas LF, Wagner KT, Shakeri A, Vosoughi D, Radisic M.   +7 more
europepmc   +1 more source

A non-traditional crystal-based compound screening method targeting the ATP binding site of Plasmodium falciparum GRP78 for identification of novel nucleoside analogues. [PDF]

Front Mol Biosci, 2022
Mrozek A, Antoshchenko T, Chen Y, Zepeda-Velázquez C, Smil D, Kumar N, Lu H, Park HW.   +7 more
europepmc   +1 more source

BowelScreen Programme Report 2012-2015

, 2017
The figures in this report relate to people invited by BowelScreen for screening between 01 October 2012 and 31 December ...
HSE National Screening Service
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

From Natural Compound Screening to Myelin-Associated Effects: Identification of Morusin as a Potent Promoter of Oligodendrocyte Differentiation. [PDF]

Int J Mol Sci
Yun W, Hong W, Oh KT, Han JH, Park K, Kim IY, Lee D, You S.   +7 more
europepmc   +1 more source

Phytochemical Compound Screening to Identify Novel Small Molecules against Dengue Virus: A Docking and Dynamics Study. [PDF]

Molecules, 2022
Shimu MSS, Mahmud S, Tallei TE, Sami SA, Adam AA, Acharjee UK, Paul GK, Emran TB, Zaman S, Uddin MS, Saleh MA, Alshehri S, Ghoneim MM, Alruwali M, Obaidullah AJ, Jui NR, Kim J, Kim B.   +17 more
europepmc   +1 more source