Results 151 to 160 of about 328,812 (261)

Epigenetic Compound Screening Uncovers Small Molecules for Reactivation of Latent HIV-1. [PDF]

Antimicrob Agents Chemother, 2020
Zutz A, Chen L, Sippl F, Humpe A, Schölz C.   +4 more
europepmc   +1 more source

Reduction of chickens use to perform <i>in vitro</i> pre-screening of novel anticoccidials by miniaturisation and increased throughput of the current <i>Eimeria tenella</i> compound-screening model. [PDF]

F1000Res, 2022
Arias-Maroto S, Aguiar-Martins K, Regidor-Cerrillo J, Ortega-Mora L, Marugan-Hernandez V.   +4 more
europepmc   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Unveiling CNS cell morphology with deep learning: A gateway to anti-inflammatory compound screening. [PDF]

PLoS One
Bahng H, Oh JP, Lee S, Yu J, Bae J, Kim EJ, Bae SH, Lee JH.   +7 more
europepmc   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Tumor organoids in cancer medicine: from model systems to natural compound screening. [PDF]

Pharm Biol
Cong R, Lu C, Li X, Xu Z, Wang Y, Sun S.
europepmc   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Head and Neck Cancer Stem Cell-Enriched Spheroid Model for Anticancer Compound Screening. [PDF]

Cells, 2020
Goričan L, Gole B, Potočnik U.
europepmc   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluation of Serum Supplementation on the Development of <i>Haemonchus contortus</i> Larvae In Vitro and on Compound Screening Results. [PDF]

Int J Mol Sci
Thilakarathne SS, Taki AC, Wang T, Nowell C, Chang BCH, Gasser RB.   +5 more
europepmc   +1 more source