Results 211 to 220 of about 359,557 (359)

UPLC-MS/MS analysis and bioactivity comparison of wild and cultivated <i>Taihangia rupestris</i> leaves: antioxidant and α-glucosidase inhibitory activities with active compound screening. [PDF]

RSC Adv
Yin JT, Wang DM, Wu XC, Lu J, Qian ZM, Li DQ, Feng R.   +6 more
europepmc   +1 more source

SCREENING OF CLASS OF PHYTOCHEMICAL COMPOUNDS AND ANTIOXIDANT AUTORADIOGRAPHIC EVALUATION IN PARIS POLYPHYLLA AND TRILLIUM GOVANIANUM USING HIGHPERFORMANCE THIN-LAYER CHROMATOGRAPHY (HPTLC)

Riddha Rashid2, Uttam Yadav2, Nitin Labhane2, Amit Saraf1*
openalex   +1 more source

Screening of the small molecule library of Meinox enables the identification of anticancer compounds in pathologically distinct cancers

, 2021
Aynura Mammadova, Arif Mermer, Fatih Kocabaş   +2 more
openalex   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening. [PDF]

Adv Healthc Mater
Lenzi E, Vertti-Quintero N, Husson J, Bulteau AL, Nizard C, Pays K, Sart S, Baroud CN.   +7 more
europepmc   +1 more source

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma. [PDF]

Sci Rep, 2021
Tuomainen K, Hyytiäinen A, Al-Samadi A, Ianevski P, Ianevski A, Potdar S, Turunen L, Saarela J, Kuznetsov S, Wahbi W, Risteli M, Mäkitie A, Monni O, Salo T.   +13 more
europepmc   +1 more source

Referee report. For: Virtual screening of zinc compounds similar to NSAIDS with better pharmacodynamic and pharmacokinetic profiles [version 1; peer review: 1 not approved]

Mohammed Hawash
openalex   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Virtual Compound Screening for Discovery of Dopamine D1 Receptor Biased Allosteric Modulators. [PDF]

J Chem Inf Model
Zhou Y, Wetsel WC, Olson SH, Barak LS.
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source