Results 41 to 50 of about 5,268 (276)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Identifying pre-service teachers' initial impressions of the concept cartoons in the school corrıdors and informal physics learning [PDF]

, 2020
CALIK, MUAMMER/0000-0001-8323-8783; Atasoy, Sengul/0000-0002-7664-1010Since concept cartoons give an important opportunity for students to achieve informal physics learning, the current research focused on pre-service teachers' initial impressions of the
Çalık, Muammer, Toksoy, Seyhan Eryılmaz, Atasoy, Şengül   +2 more
core   +1 more source

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Michele D'Orazio, Biagio Palmisano, Silvia Franco, Arianna Mencattini, Roberta Angelini, Eugenio Martinelli, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +17 more
wiley   +1 more source

A Novel Concept of a Cartoon-Generator Application on a Mobile Phone

International Journal of Interactive Mobile Technologies (iJIM), 2010
In this work the development and deployment of a new concept of cartoon-generation on a mobile phone is presented. An interactive multimedia application was designed for a push-approach of sending short e-cartoons from a mobile phone to a central WEB server. The concept of a unique cartoon-generator will be discussed.
Stergar, Janez, Šuli?, Andrija, Silva, Bruno Rodrigues   +2 more
openaire   +3 more sources

Interactieve Concept Cartoons

, 2020
Interactieve concept cartoons stimuleren kinderen om kritisch na te denken over maatschappelijke onderwerpen waar natuurwetenschappelijke kennis aan ten grondslag ligt. Samen met het werkblad en de bronnen vormen de cartoons een didactisch instrument. De
Bredeweg, Bert, Kruit, Patricia
core  

Clustomesogen Showing Sub‐Zero Liquid Crystal Properties: Supramolecular Assembly Between Cs2[Mo6Ii8(OCOC2F5)6] and Hexaethylenoxide Containing Mesogenic Dimers

Advanced Materials, EarlyView.
Associating a red‐NIR phosphorescent octahedral hexanuclear molybdenum cluster compound with hexaethyleneoxide chains bearing mesogenic units on both ends leads to an emissive hybrid liquid crystal showing mesomorphism on a very unusual temperature range down to −25°C.
Killiann Heinz, Jeanne Rebours, Zoulikha Zerrouqi, Noée Dumait, Maria Amela‐Cortes, Nikolai Scheuring, Sara Simonovska, Sebastian Marino, Max Ebert, Stéphane Cordier, Sabine Laschat, Yann Molard   +11 more
wiley   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Concept Cartoons tasks as a complement to mathematical textbooks

, 2021
This work deals with tasks in the Concept Cartoons format. The work presents the use of tasks during the teaching of mathematics at the second stage of primary school.
ČECH, Adam
core  

Concept cartoons as discursive-reflective scenarios to activate procedural understanding in inquiry learning [PDF]

, 2016
Der Erwerb von Kompetenzen naturwissenschaftlicher Erkenntnisgewinnung und des Wissenschaftlichen Denkens ist ein zentrales Bildungsziel des naturwissenschaftlichen Unterrichts.
Arnold, Julia, Mayer, Jürgen, Kremer, Kerstin   +2 more
core   +1 more source