Results 91 to 100 of about 622,206 (305)
Challenges and Opportunities of Creating Conceptual Maps. [PDF]
AJOB Neurosci, 2021 Cabrera LY, Bluhm R.
europepmc +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Mapas conceituais e questionários: uso ferramentas de avaliação do ensino em ações de extensão
Revista de Estudos e Pesquisas sobre Ensino Tecnológico, 2017 The integration of teaching, research and extension is an efficient didactic model in the agrarian sciences. Final students of the Technical Course on Fishery Resources followed the traditional process of fish meal production in the rural community Nossa
Rogério Ferreira Nakauth +2 more
doaj
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Using conceptual maps in physics classes [PDF]
, 2004 Concept Maps: Theory, Methodology, Technology Proc. of the First Int. Conference on Concept Mapping A. J. Cañas, J. D. Novak, F. M. González, Eds. Pamplona, Spain 2004This Poster follows, on the one hand, from the long-term use of concept maps in ...
Fonseca, F. +2 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Ulisses: um navegador conceptual para topic maps [PDF]
, 2005 A norma ISO-IEC 13250 – Topic Maps – faz a ponte entre os domínios de representação de conhecimento e gestão de informação. Tópicos e associações formam uma rede semântica estruturada sobre os recursos de informação.
Henriques, Pedro Rangel +2 more
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Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Conceptual Maps: A Resource for the Supported Learning in Technologies [PDF]
, 2007 Se describen las características fundamentales de los mapas conceptuales, se resalta su importancia como instrumento para la organización y sistematización de ideas y conocimientos y se ofrecen propuestas para su elaboración, especialmente ...
Menéndez, Luis M. +2 more
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