Results 131 to 140 of about 4,930 (171)

Complex rheology of condensin in entangled DNA

open access: yes
Conforto F   +3 more
europepmc   +1 more source

Condensin I confers Stiffness and Centromeric Cohesion to Mitotic Chromosomes

open access: yes
Nielsen CF   +9 more
europepmc   +1 more source

Condensin II activation by M18BP1

open access: yesMolecular Cell
ABSTRACT Condensin complexes promote the drastic spatial rearrangement of the genome upon mitotic entry. Condensin II initiates chromosome condensation in early mitosis. To prevent chromosome condensation during interphase, condensin II is inhibited by MCPH1, but the mechanism is unknown.
Erin E Cutts
exaly   +5 more sources
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Condensin, master organizer of the genome

Chromosome Research, 2017
A fundamental requirement in nature is for a cell to correctly package and divide its replicated genome. Condensin is a mechanical multisubunit complex critical to this process. Condensin uses ATP to power conformational changes in DNA to enable to correct DNA compaction, organization, and segregation of DNA from the simplest bacteria to humans.
Paul Kalitsis   +2 more
exaly   +3 more sources

Condensin Regulation of Genome Architecture

Journal of Cellular Physiology, 2017
Condensin complexes exist across all domains of life and are central to the structure and organization of chromatin. As architectural proteins, condensins control chromatin compaction during interphase and mitosis. Condensin activity has been well studied in mitosis but have recently emerged as important regulators of genome organization and gene ...
Vibhuti, Rana, Giovanni, Bosco
openaire   +2 more sources

Condensin: crafting the chromosome landscape

Chromosoma, 2013
The successful transmission of complete genomes from mother to daughter cells during cell divisions requires the structural re-organization of chromosomes into individualized and compact structures that can be segregated by mitotic spindle microtubules. Multi-subunit protein complexes named condensins play a central part in this chromosome condensation
Ilaria, Piazza   +2 more
openaire   +2 more sources

Biochemical Analysis of Bacterial Condensins

2017
Condensins help establish compactness of bacterial chromosomes and assist in their segregation during cell growth and division. They act as elaborate macromolecular machines that organize the chromosome on a global scale and link it to the pan-cell dynamics. The mechanism of condensins in its entirety is yet to be elucidated.
Zoya M, Petrushenko   +1 more
openaire   +2 more sources

Differential Contributions of Condensin I and Condensin II to Mitotic Chromosome Architecture in Vertebrate Cells [PDF]

open access: yesCell, 2003
The canonical condensin complex (henceforth condensin I) plays an essential role in mitotic chromosome assembly and segregation from yeast to humans. We report here the identification of a second condensin complex (condensin II) from vertebrate cells.
Ana Losada, Andrew Neuwald, Takao Ono
exaly   +3 more sources

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