Results 131 to 140 of about 4,930 (171)
Condensin I confers Stiffness and Centromeric Cohesion to Mitotic Chromosomes
Nielsen CF +9 more
europepmc +1 more source
Condensin II activation by M18BP1
ABSTRACT Condensin complexes promote the drastic spatial rearrangement of the genome upon mitotic entry. Condensin II initiates chromosome condensation in early mitosis. To prevent chromosome condensation during interphase, condensin II is inhibited by MCPH1, but the mechanism is unknown.
Erin E Cutts
exaly +5 more sources
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Condensin, master organizer of the genome
Chromosome Research, 2017A fundamental requirement in nature is for a cell to correctly package and divide its replicated genome. Condensin is a mechanical multisubunit complex critical to this process. Condensin uses ATP to power conformational changes in DNA to enable to correct DNA compaction, organization, and segregation of DNA from the simplest bacteria to humans.
Paul Kalitsis +2 more
exaly +3 more sources
Condensin Regulation of Genome Architecture
Journal of Cellular Physiology, 2017Condensin complexes exist across all domains of life and are central to the structure and organization of chromatin. As architectural proteins, condensins control chromatin compaction during interphase and mitosis. Condensin activity has been well studied in mitosis but have recently emerged as important regulators of genome organization and gene ...
Vibhuti, Rana, Giovanni, Bosco
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Condensin: crafting the chromosome landscape
Chromosoma, 2013The successful transmission of complete genomes from mother to daughter cells during cell divisions requires the structural re-organization of chromosomes into individualized and compact structures that can be segregated by mitotic spindle microtubules. Multi-subunit protein complexes named condensins play a central part in this chromosome condensation
Ilaria, Piazza +2 more
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Biochemical Analysis of Bacterial Condensins
2017Condensins help establish compactness of bacterial chromosomes and assist in their segregation during cell growth and division. They act as elaborate macromolecular machines that organize the chromosome on a global scale and link it to the pan-cell dynamics. The mechanism of condensins in its entirety is yet to be elucidated.
Zoya M, Petrushenko +1 more
openaire +2 more sources
Differential Contributions of Condensin I and Condensin II to Mitotic Chromosome Architecture in Vertebrate Cells [PDF]
The canonical condensin complex (henceforth condensin I) plays an essential role in mitotic chromosome assembly and segregation from yeast to humans. We report here the identification of a second condensin complex (condensin II) from vertebrate cells.
Ana Losada, Andrew Neuwald, Takao Ono
exaly +3 more sources

