Results 111 to 120 of about 6,249 (200)

Condensin, Chromatin Crossbarring and Chromosome Condensation

open access: yes, 2012
The processes underlying the large-scale reorganisation of chromatin in mitosis that form compact mitotic chromosomes and ensure the fidelity of chromosome segregation during cell division still remain obscure.
Heeger, Sebastian   +2 more
core   +1 more source

Condensin IDC, DPY-21, and CEC-4 maintain X chromosome repression in C. elegans.

open access: yesPLoS Genetics
Dosage compensation in Caenorhabditis elegans equalizes X-linked gene expression between XX hermaphrodites and XO males. The process depends on a condensin-containing dosage compensation complex (DCC), which binds the X chromosomes in hermaphrodites to ...
Jessica Trombley   +4 more
doaj   +1 more source

Chromosome compaction is triggered by an autonomous DNA-binding module within condensin

open access: yesCell Reports
Summary: The compaction of chromatin into mitotic chromosomes is essential for faithful transmission of the genome during cell division. In eukaryotes, chromosome morphogenesis is regulated by the condensin complex, though the exact mechanism used to ...
Alyssa Pastic   +5 more
doaj   +1 more source

Cdk1-dependent phosphorylation of KIF4A at S1186 triggers lateral chromosome compaction during early mitosis.

open access: yesPLoS ONE, 2018
Chromosome organization during cell division is achieved through the timely association of proteins with chromatin and is regulated by protein phosphorylation.
Hideaki Takata   +3 more
doaj   +1 more source

Condensin wraps it up

open access: yesThe Journal of Cell Biology, 2002
![][1] Condensin introduces supercoils (left) by wrapping DNA around itself (right). Hirano/Elsevier Packing DNA into a nucleus is no mean feat. Now, David Bazett-Jones (Hospital for Sick Children, Toronto, Canada), Keiji Kimura, and Tatsuya Hirano (Cold Spring Harbor Laboratory,
openaire   +2 more sources

Chromosome Dynamics: The Case of the Missing Condensin

open access: yes, 2009
SummaryCondensins are conserved protein complexes that play integral roles in chromosome dynamics during mitosis and meiosis. Caenorhabditis elegans has been thought to be unusual in that it appeared to lack a typical condensin I complex. However, recent
Ford, Jason R., Schumacher, Jill M.
core   +1 more source

An investigation into factors affecting condensin association with mitotic centromeres

open access: yes, 2017
The SMC protein family (Structural Maintenance of Chromosomes) consists of a group of highly conserved protein complexes, central to chromosome dynamics and key cell cycle events.
Catrina Anne Miles (16243238)
core   +1 more source

Molecular mechanism targeting condensin for chromosome condensation

open access: yesThe EMBO Journal
Genomes are organised into DNA loops by the Structural Maintenance of Chromosomes (SMC) proteins. SMCs establish functional chromosomal sub-domains for DNA repair, gene expression and chromosome segregation, but how SMC activity is specifically targeted ...
Menglu Wang   +5 more
doaj   +1 more source

Construction and characterisation of CAP-H/condensin I and CAP-D3/condensin II conditional knockout DT40 cells

open access: yes, 2012
© 2012 Dr. Lydia Crystal GreenThe condensins are essential protein complexes that are required for correct organisation and division of chromosomes during mitosis. Two condensin complexes exist in higher eukaryotes, condensin I and condensin II.
Green, Lydia Crystal
core  

Real-time imaging of DNA loop extrusion by condensin

open access: yes, 2018
It has been hypothesized that SMC protein complexes such as condensin and cohesin spatially organize chromosomes by extruding DNA into large loops. We directly visualized the formation and processive extension of DNA loops by yeast condensin in real time.
Shaltiel, Indra A. (author)   +24 more
core   +1 more source

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