Results 91 to 100 of about 4,930 (171)

Chromosome compaction is triggered by an autonomous DNA-binding module within condensin

Cell Reports
Summary: The compaction of chromatin into mitotic chromosomes is essential for faithful transmission of the genome during cell division. In eukaryotes, chromosome morphogenesis is regulated by the condensin complex, though the exact mechanism used to ...
Alyssa Pastic, Michael L. Nosella, Annahat Kochhar, Zi Hao Liu, Julie D. Forman-Kay, Damien D’Amours   +5 more
doaj   +1 more source

Condensin wraps it up

The Journal of Cell Biology, 2002
![][1] Condensin introduces supercoils (left) by wrapping DNA around itself (right). Hirano/Elsevier Packing DNA into a nucleus is no mean feat. Now, David Bazett-Jones (Hospital for Sick Children, Toronto, Canada), Keiji Kimura, and Tatsuya Hirano (Cold Spring Harbor Laboratory,
openaire   +2 more sources

Condensin II interacts with BLM helicase in S phase to maintain genome stability

Communications Biology
Vertebrates possess two condensins, I and II, that are essential for chromosome condensation and segregation. Condensin II has also been implicated in maintaining genome integrity outside of mitosis, though the underlying mechanisms are unclear. Here, we
Brian Rodemoyer, Ganesha Kariyawasam, Veena Subramanian, Kristina Schmidt   +3 more
doaj   +1 more source

Molecular mechanism targeting condensin for chromosome condensation

The EMBO Journal
Genomes are organised into DNA loops by the Structural Maintenance of Chromosomes (SMC) proteins. SMCs establish functional chromosomal sub-domains for DNA repair, gene expression and chromosome segregation, but how SMC activity is specifically targeted ...
Menglu Wang, Daniel Robertson, Juan Zou, Christos Spanos, Juri Rappsilber, Adele L Marston   +5 more
doaj   +1 more source

Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster

Nature Communications
Neural stem and progenitor cell (NSPC) maintenance is essential for ensuring that organisms are born with proper brain volumes and head sizes. Microcephaly is a disorder in which babies are born with significantly smaller head sizes and cortical volumes.
Bert I. Crawford, Mary Jo Talley, Joshua Russman, James Riddle, Sabrina Torres, Troy Williams, Michelle S. Longworth   +6 more
doaj   +1 more source

Condensin IDC has a functional ATPase that is required for X-Chromosome dosage compensation in C. elegans. [PDF]

Genetics
Chawla B, Jatia S, Sloan D, Eduful J, Mendoza H, McClear CA, Tran J, Csankovszki G.   +7 more
europepmc   +1 more source

A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination. [PDF]

Nucleic Acids Res
Balan T, Bazin-Gélis M, Guérineau M, Vitali V, Zangarelli C, Arnaiz O, Abbou L, Altair A, Boutte du Jonchay A, Camprodon A, Giovannetti M, Poitrenaud C, Schumacher E, Bischerour J, Tassin AM, Régnier V, Chevreux G, Duharcourt S, Bétermier M.   +18 more
europepmc   +1 more source

Condensin accelerates long-range intra-chromosomal interactions. [PDF]

Nat Commun
Zou F, Li Y, Földes T, Pinholt HD, Smith C, Mirny L, Bai L.   +6 more
europepmc   +1 more source

Comprehensive bioinformatics analysis of NCAPH expression and its clinical importance in endometrial cancer. [PDF]

Oncol Lett
Huang Y, Kang K, Zhuo Q, Ma Q, Xue Y, Zhu Y, Huang M.   +6 more
europepmc   +1 more source

Investigations into multiple fission yeast chromosome size determinants. [PDF]

J Cell Sci
Wu PS, Fallesen T, Uhlmann F.
europepmc   +1 more source