Results 81 to 90 of about 6,725 (195)
Molecular Ecology, Volume 35, Issue 16, August 2026.ABSTRACT Urbanization has become one of the leading causes of habitat transformation affecting ecosystem functioning. However, the transcriptomic response to urbanization remains poorly understood. Here, we conducted a transcriptomic analysis along an urbanization gradient under different warming temperatures.
Katarzyna Dudek, Guillaume Wos
wiley +1 more source
Structural Studies of DNA-bound Condensin [PDF]
Eukaryotic chromosomes undergo massive three-dimensional rearrangements over the course of the cell cycle. Prior to cell division, chromosomes are condensed into rod-shaped structures which ensures the faithful transmission of the genetic material into ...
Lecomte, Léa Candice Lucie
core +1 more source
Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling [PDF]
Open Biology, 2015 SMC proteins are essential components of three protein complexes that are important for chromosome structure and function. The cohesin complex holds replicated sister chromatids together, whereas the condensin complex has an essential role in mitotic ...
Helena Barysz +6 more
doaj +1 more source
Factors Determining Sirtuin‐1 Target Engagement
Advanced Biology, Volume 10, Issue 7, July 2026.ABSTRACT Sirtuin‐1 (Sirt1) is a key NAD+‐dependent deacylase regulating metabolism, stress responses, genome stability, and aging. Although well‐characterized biochemically and structurally, its substrate selectivity remains unclear: in vitro, Sirt1 appears promiscuous, while in vivo it activates particular processes in response to different stimuli ...
Petra Neumann‐Staubitz +3 more
wiley +1 more source
Multiple roles of Condensins: a complex story [PDF]
Biology of the Cell, 2004 Summry— Condensins are pentameric complexes that were initially described as being involved in the dynamics of chromosomes during mitosis. It has been recently established that two related complexes (Condensin I and Condensin II) contribute to this process.
Legagneux, Vincent +2 more
openaire +2 more sources
Clinical Case Reports, Volume 14, Issue 7, July 2026.Serial sagittal T1‐weighted MR images demonstrating persistent thinning of the corpus callosum. (A) Initial MRI at 19 months of age shows diffuse thinning of the corpus callosum involving the body and splenium. (B) Follow‐up MRI one year later demonstrates stable appearance without interval progression, consistent with corpus callosal hypoplasia ...
Anwar Abu Hetta +4 more
wiley +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, Volume 45, Issue 4, Page 644-671, July/August 2026.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Condensins and 3D Organization of the Interphase Nucleus [PDF]
Current Genetic Medicine Reports, 2013 Condensins are conserved multi-subunit protein complexes that participate in eukaryotic genome organization. Well known for their role in mitotic chromosome condensation, condensins have recently emerged as integral components of diverse interphase processes. Recent evidence shows that condensins are involved in chromatin organization, gene expression,
Heather A, Wallace, Giovanni, Bosco
openaire +2 more sources
Condensin I protects meiotic cohesin from WAPL-1 mediated removal.
PLoS Genetics, 2018 Condensin complexes are key determinants of higher-order chromatin structure and are required for mitotic and meiotic chromosome compaction and segregation.
Margarita R Hernandez +5 more
doaj +1 more source
Condensin II and GAIT complexes cooperate to restrict LINE-1 retrotransposition in epithelial cells. [PDF]
PLoS Genetics, 2017 LINE-1 (L1) retrotransposons can mobilize (retrotranspose) within the human genome, and mutagenic de novo L1 insertions can lead to human diseases, including cancers. As a result, cells are actively engaged in preventing L1 retrotransposition.
Jacqueline R Ward +9 more
doaj +1 more source