Results 61 to 70 of about 7,152 (199)

Impact of Methylparaben on Cumulus Cell DNA Integrity and Porcine Oocyte Developmental Competence In Vitro

Journal of Applied Toxicology, Volume 46, Issue 9, Page 2985-2996, September 2026.
ABSTRACT Parabens (PBs) are compounds widely used as preservatives in personal care products, food, and pharmaceuticals. Methylparaben (MePB) is the most used by different industries due to its chemical properties and low cost. The high daily human exposure to these compounds has raised concerns about their potential effects on health, particularly on ...
Yenny Ramírez‐Jara, Brenda Casado, Miguel Betancourt, Adyeni Barajas‐Salinas, Eduardo Casas, Gabriela Hurtado‐Alvarado, Juan José Rodríguez‐Mercado, Alma López, Iván Bahena, Lizbeth Juárez‐Rojas, Leticia González‐Núñez, Fahiel Casillas   +11 more
wiley   +1 more source

The molecular mechanism of condensin in mitotic chromosome formation [PDF]

, 2022
The rearrangement of interphase chromatin into mitotic chromosomes is crucial for faithful chromosome segregation. Defects in this process may cause chromosome entanglement, decompaction, chromosome bridges during anaphase, and eventually genome ...
Tang, Minzhe
core   +1 more source

Homologous recombination mutants cause differing lethality between h− and h+ Schizosaccharomyces pombe strains due to mat1 heterochromatin

The FEBS Journal, Volume 293, Issue 17, Page 5205-5220, September 2026.
Homologous recombination (HR) in Schizosaccharomyces pombe is essential when mating‐type switching–induced double‐strand breaks (DSBs) form at the mat1 locus. In h90 and h− strains, efficient mat1 DSB formation renders HR indispensable unless suppressors block these breaks.
Peter Kolesar, Siarhei Paliavoi, Barbora Stefanovie, Jan Josef Palecek   +3 more
wiley   +1 more source

Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin [PDF]

Proceedings of the National Academy of Sciences, 2004
Condensin is a conserved five-subunit complex containing two SMC (structural maintenance of chromosomes) and three non-SMC subunits and plays a major role in mitotic chromosome condensation. Condensin also acts in interphase and is required for DNA repair and replication checkpoint control. We attempted to study the function of the condensin in greater
Ee Sin, Chen, Takashi, Sutani, Mitsuhiro, Yanagida   +2 more
openaire   +2 more sources

Estimation of chloroplast macromolecular complex copy numbers and subunit stoichiometries during the Chlamydomonas reinhardtii cell cycle

The Plant Journal, Volume 127, Issue 5, September 2026.
SUMMARY An unbiased, quantitative view of biomolecules in a living cell is a prerequisite for accurate modeling approaches and informs our understanding of cellular metabolism at scale. In this work, we used the total protein approach (TPA), in which the total protein mass of a given proteomics sample is used as a calibrator for absolute protein ...
Stefan Schmollinger, Daniela Strenkert, Samuel O. Purvine, Carrie D. Nicora, Eric Soubeyrand, Gilles J. Basset, Sabeeha S. Merchant   +6 more
wiley   +1 more source

The interaction between KIF4A and condensin I.

, 2018
(A) HeLa cells expressing EGFP-KIF4A WT or S1186 were arrested at mitosis and the KIF4A-condensin I complex was recovered by immunoprecipitation against GFP and SMC2.
Kiichi Fukui (2036467), Hideaki Takata (468699), Marliza Madung (6111434), Kaoru Katoh (6111437)   +3 more
core   +1 more source

Geometric partitioning of cohesin and condensin is a consequence of chromatin loops [PDF]

, 2018
SMC (structural maintenance of chromosomes) complexes condensin and cohesin are crucial for proper chromosome organization. Condensin has been reported to be a mechanochemical motor capable of forming chromatin loops, while cohesin passively diffuses ...
Friedman, B., Doshi, A., Yeh, E., Lawrimore, J., Bloom, K.   +4 more
core   +1 more source

Transcriptional repression during spermatogenesis in C. elegans requires TOP-2, condensin II, and the MET-2 H3K9 methyltransferase.

microPublication Biology, 2023
In C. elegans RNA polymerase II (RNAPII) transcription is globally repressed as oocytes prepare for meiosis. Recent work has identified the transcriptional repressors responsible for genome silencing in oocytes, and they are topoisomerase II (TOP-2 ...
Emilie Chien, W. Matthew Michael
doaj   +1 more source

The evolving landscape of the Warburg effect in gastric cancer: From molecular mechanisms to targeted therapy

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Hypoxia, oncogenic signaling, transcriptional and epigenetic remodeling, and H. pylori–microbiota interactions drive the Warburg effect in gastric cancer. Enhanced glycolysis and lactate export support biosynthesis, remodel the tumor microenvironment, promote stromal activation and immune suppression, and reveal actionable biomarkers and therapeutic ...
Guanmo Liu, Pan Li, Zizhuo Li, Jie Li, Chenggang Zhang, Yihua Wang, Weiming Kang, Xin Ye   +7 more
wiley   +1 more source

Condensin function in dosage compensation [PDF]

Epigenetics, 2009
Dosage compensation is an essential process that equalizes X-linked gene dosage between the sexes. In the worm Caenorhabditis elegans, a complex of proteins called the dosage compensation complex (DCC) binds both X chromosomes in hermaphrodites to downregulate gene expression two-fold and hence to reduce X-linked gene expression levels equal to that in
openaire   +2 more sources