Results 51 to 60 of about 7,152 (199)
Condensins are Required for Maintenance of Nuclear Architecture [PDF]
Cells, 2014 The 3-dimensional spatial organization of eukaryotic genomes is important for regulation of gene expression as well as DNA damage repair. It has been proposed that one basic biophysical property of all nuclei is that interphase chromatin must be kept in a condensed prestressed state in order to prevent entropic pressure of the DNA polymer from ...
George, Carolyn +3 more
openaire +3 more sources
RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes. [PDF]
PLoS Genetics, 2014 Condensin-mediated chromosome condensation is essential for genome stability upon cell division. Genetic studies have indicated that the association of condensin with chromatin is intimately linked to gene transcription, but what transcription-associated
Pénélope Legros +4 more
doaj +1 more source
Condensin-Condensin Interactions Facilitate Mitotic Chromosome Assembly in Xenopus Egg Extracts. [PDF]
Genes CellsABSTRACT Condensins are large protein complexes that play a central role in mitotic chromosome assembly in eukaryotes. Our previous mutational analyses of condensin I, combined with Xenopus egg cell‐free extracts, provided evidence that dynamic condensin‐condensin ...
Kinoshita K, Aizawa Y, Hirano T.
europepmc +4 more sources
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Biallelic variants in NSMCE2 (MMS21), which encodes the SUMO E3 ligase subunit of the SMC5/6 chromatin‐maintenance complex, have recently been implicated in microcephalic primordial dwarfism (MPD), corresponding to Seckel syndrome type 10 (OMIM #617246).
Cristina Peduto +5 more
wiley +1 more source
Dangerous liaisons: MYCN meets condensins [PDF]
Cell Cycle, 2014 (2014). Dangerous liaisons: MYCN meets condensins. Cell Cycle: Vol. 13, No. 8, pp. 1225-1226.
Y. J. Achar, M. Foiani
openaire +3 more sources
RNA polymerase backtracking results in the accumulation of fission yeast condensin at active genes
Life Science Alliance, 2021 Using both experiments and mathematical modelling, the authors show that RNA polymerase backtracking contributes to the accumulation of condensin in the termination zone of active genes.
Julieta Rivosecchi +5 more
doaj +1 more source
Single‐Nucleus Transcriptome Analysis Provides New Insights Into B Chromosome Elimination in Sorghum
Plant Biotechnology Journal, Volume 24, Issue 11, Page 5719-5728, November 2026.ABSTRACT B chromosomes are supernumerary entities found in many plant species, with some exhibiting tissue‐specific elimination. In Sorghum purpureosericeum, extensive B chromosome elimination occurs during embryogenesis affecting most of the embryonic organs, leaving the B chromosome maintained mainly in limited regions of meristems.
T. Bojdová +4 more
wiley +1 more source
Chromosome Shaping by Two Condensins [PDF]
Cell Cycle, 2004 It remains a big challenge in modern cell biology to determine the mechanism by which a discrete set of rod-shaped chromosomes is assembled from an amorphous mass of interphase chromatin. Recent studies start to shed new lights on how this process is actively supported by a class of multiprotein complexes called condensins.
openaire +2 more sources
Taking cohesin and condensin in context
PLOS Genetics, 2018 Structural maintenance of chromosome (SMC) protein complexes, including cohesin and condensin, are increasingly being recognized for their important role in cancer and development, making it critical that we understand how these evolutionarily conserved multi-subunit protein complexes associate with and organize the genome.
Kobe C. Yuen, Jennifer L. Gerton
openaire +3 more sources
Metaphase chromosome structure is dynamically maintained by condensin I-directed DNA (de)catenation
eLife, 2017 Mitotic chromosome assembly remains a big mystery in biology. Condensin complexes are pivotal for chromosome architecture yet how they shape mitotic chromatin remains unknown.
Ewa Piskadlo +2 more
doaj +1 more source