Results 51 to 60 of about 6,249 (200)
Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans
eLife, 2022 Condensins are molecular motors that compact DNA via linear translocation. In Caenorhabditis elegans, the X-chromosome harbors a specialized condensin that participates in dosage compensation (DC).
Jun Kim +9 more
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Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast.
PLoS Genetics, 2020 Correct bioriented attachment of sister chromatids to the mitotic spindle is essential for chromosome segregation. In budding yeast, the conserved protein shugoshin (Sgo1) contributes to biorientation by recruiting the protein phosphatase PP2A-Rts1 and ...
Galal Yahya +7 more
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Condensin goes with the family but not with the flow [PDF]
Genome Biology, 2008 Condensin and cohesin are loaded onto yeast chromosomes by a common mechanism at RNA polymerase III transcribed genes. Whereas cohesin translocates from these loading sites to mediate cohesion at secondary locations, condensin remains, bringing distant sites together into clusters.
Gartenberg, MR, Merkenschlager, M
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Condensin ATPase motifs contribute differentially to the maintenance of chromosome morphology and genome stability. [PDF]
PLoS Biology, 2018 Effective transfer of genetic information during cell division requires a major reorganization of chromosome structure. This process is triggered by condensin, a conserved pentameric ATPase essential for chromosome condensation.
Roger Palou +5 more
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Condensins: Organizing and Segregating the Genome [PDF]
Current Biology, 2005 Condensins are multi-subunit protein complexes that play a central role in mitotic chromosome assembly and segregation. The complexes contain 'structural maintenance of chromosomes' (SMC) ATPase subunits, and induce DNA supercoiling and looping in an ATP-hydrolysis-dependent manner in vitro.
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RNA processing factors Swd2.2 and Sen1 antagonize RNA Pol III-dependent transcription and the localization of condensin at Pol III genes. [PDF]
PLoS Genetics, 2014 Condensin-mediated chromosome condensation is essential for genome stability upon cell division. Genetic studies have indicated that the association of condensin with chromatin is intimately linked to gene transcription, but what transcription-associated
Pénélope Legros +4 more
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Structure of the condensin holo complex [PDF]
, 2021 Division of one mother cell into two daughter cells resides at the very core of living organisms. To ensure that the cell’s genetic material is equally segregated into both daughter cells, cells undergo a sophisticated succession of highly controlled ...
Merkel, Fabian
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The loading of condensin in the context of chromatin
Current Genetics, 2016 The packaging of DNA into chromosomes is a ubiquitous process that enables living organisms to structure and transmit their genome accurately through cell divisions. In the three kingdoms of life, the architecture and dynamics of chromosomes rely upon ring-shaped SMC (Structural Maintenance of Chromosomes) condensin complexes.
Robellet, Xavier +2 more
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Nucleus, 2019 Plants possess the structural maintenance of chromosome (SMC) protein complexes cohesin, condensin, and SMC5/6, which function in fundamental biological processes such as sister chromatid cohesion, chromosome condensation and segregation, and damaged DNA
Takuya Sakamoto +3 more
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Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. [PDF]
PLoS Genetics, 2014 During development of the cerebral cortex, neural stem cells (NSCs) divide symmetrically to proliferate and asymmetrically to generate neurons. Although faithful segregation of mitotic chromosomes is critical for NSC divisions, its fundamental mechanism ...
Kenji Nishide, Tatsuya Hirano
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