Results 31 to 40 of about 4,930 (171)
eLife, 2023 The localization of condensin along chromosomes is crucial for their accurate segregation in anaphase. Condensin is enriched at telomeres but how and for what purpose had remained elusive.
Léonard Colin +12 more
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Condensin I reveals new insights on mouse meiotic chromosome structure and dynamics. [PDF]
PLoS ONE, 2007 Chromosome shaping and individualization are necessary requisites to warrant the correct segregation of genomes in either mitotic or meiotic cell divisions. These processes are mainly prompted in vertebrates by three multiprotein complexes termed cohesin
Alberto Viera +6 more
doaj +1 more source
Condensin-Condensin Interactions Facilitate Mitotic Chromosome Assembly in Xenopus Egg Extracts. [PDF]
Genes CellsABSTRACT Condensins are large protein complexes that play a central role in mitotic chromosome assembly in eukaryotes. Our previous mutational analyses of condensin I, combined with Xenopus egg cell‐free extracts, provided evidence that dynamic condensin‐condensin ...
Kinoshita K, Aizawa Y, Hirano T.
europepmc +4 more sources
Cell-Cycle Regulation of Dynamic Chromosome Association of the Condensin Complex
Cell Reports, 2018 Summary: Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from the compaction of interphase chromatin by the condensin complex. Condensin is a member of the structural maintenance of chromosomes (SMC) family of ATPases,
Rahul Thadani +4 more
doaj +1 more source
Interdependency and phosphorylation of KIF4 and condensin I are essential for organization of chromosome scaffold. [PDF]
PLoS ONE, 2017 Kinesin family member 4 (KIF4) and condensins I and II are essential chromosomal proteins for chromosome organization by locating primarily to the chromosome scaffold.
Rawin Poonperm +3 more
doaj +1 more source
Cell Reports, 2015 Condensin is a conserved chromosomal complex necessary to promote mitotic chromosome condensation and sister chromatid resolution during anaphase. Here, we report that yeast condensin binds to replicated centromere regions.
Joanne Leonard +6 more
doaj +1 more source
A new family of bacterial condensins [PDF]
Molecular Microbiology, 2011 SummaryCondensins play a central role in global chromatin organization. In bacteria, two families of condensins have been identified, the MukBEF and SMC–ScpAB complexes. Only one of the two complexes is usually found in a given species, giving rise to a paradigm that a single condensin organizes bacterial chromosomes.
Zoya M, Petrushenko +2 more
openaire +2 more sources
Nucleic Acids Research, 2022 Abstract Condensin I and condensin II are multi-subunit complexes that are known for their individual roles in genome organization and preventing genomic instability. However, interactions between condensin I and condensin II subunits and cooperative roles for condensin I and condensin II, outside of their genome organizing functions ...
Jacqueline R Ward +7 more
openaire +2 more sources
MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface
eLife, 2021 Dramatic change in chromosomal DNA morphology between interphase and mitosis is a defining features of the eukaryotic cell cycle. Two types of enzymes, namely cohesin and condensin confer the topology of chromosomal DNA by extruding DNA loops.
Martin Houlard +9 more
doaj +1 more source
Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast.
PLoS Genetics, 2020 Correct bioriented attachment of sister chromatids to the mitotic spindle is essential for chromosome segregation. In budding yeast, the conserved protein shugoshin (Sgo1) contributes to biorientation by recruiting the protein phosphatase PP2A-Rts1 and ...
Galal Yahya +7 more
doaj +1 more source