Results 31 to 40 of about 6,725 (195)

Chromosome Organization: Original Condensins [PDF]

Current Biology, 2014
Two new studies reveal the main actors involved in the resolution and segregation of newly replicated origins in bacteria. These results have important implications for our understanding of the mechanisms involved in precisely coordinating chromosome organization, segregation and replication.
Diego I. Cattoni, Antoine Le Gall, Marcelo Nöllmann   +2 more
openaire   +2 more sources

Fob1-dependent condensin recruitment and loop extrusion on yeast chromosome III.

PLoS Genetics, 2023
Despite recent advances in single-molecule and structural analysis of condensin activity in vitro, mechanisms of functional condensin loading and loop extrusion that lead to specific chromosomal organization remain unclear.
Manikarna Dinda, Ryan D Fine, Shekhar Saha, Zhenjia Wang, Chongzhi Zang, Mingguang Li, Jeffrey S Smith   +6 more
doaj   +1 more source

Condensin-driven loop extrusion on supercoiled DNA

, 2022
Condensin, a structural maintenance of chromosomes (SMC) complex, has been shown to be a molecular motor protein that organizes chromosomes by extruding loops of DNA.
Pradhan, B., van der Torre, J., Dekker, C., Martin Gonzalez, A. (author), Kim, E. (author), van der Torre, J. (author), Kim, E., Pradhan, B. (author), Martin Gonzalez, A., Dekker, C. (author)   +9 more
core   +3 more sources

Contrasting roles of condensin I and condensin II in mitotic chromosome formation [PDF]

, 2012
© 2012. Published by The Company of Biologists LtdIn vertebrates, two condensin complexes exist, condensin I and condensin II, which have differing but unresolved roles in organizing mitotic chromosomes.
Choo, KH, Vagnarelli, P, Turnbull, L, Cipetic, M, Hudson, DF, Whitchurch, CB, Kim, JH, Chang, TM, Choo, KHA, Kalitsis, P, Green, LC, Marshall, O, Samejima, K, Earnshaw, WC   +13 more
core   +1 more source

Plasmodium Condensin Core Subunits SMC2/SMC4 Mediate Atypical Mitosis and Are Essential for Parasite Proliferation and Transmission

Cell Reports, 2020
Summary: Condensin is a multi-subunit protein complex regulating chromosome condensation and segregation during cell division. In Plasmodium spp., the causative agent of malaria, cell division is atypical and the role of condensin is unclear.
Rajan Pandey, Steven Abel, Matthew Boucher, Richard J. Wall, Mohammad Zeeshan, Edward Rea, Aline Freville, Xueqing Maggie Lu, Declan Brady, Emilie Daniel, Rebecca R. Stanway, Sally Wheatley, Gayani Batugedara, Thomas Hollin, Andrew R. Bottrill, Dinesh Gupta, Anthony A. Holder, Karine G. Le Roch, Rita Tewari   +18 more
doaj   +1 more source

The expanding territories of condensin II [PDF]

Cell Cycle, 2015
The 3D structure of the eukaryotic genome and its spatial regulation within nuclei are governed by a range of architectural proteins. One class of such factors is the condensins, highly conserved multi-subunit protein complexes. Most eukaryotic species have 2 condensins, condensin I and II, and both condensins are essential for mitotic chromosome ...
Yoko Ito, Masashi Narita
openaire   +3 more sources

Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα [PDF]

, 2012
© 2012 Samejima et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication dateMitotic chromosome formation involves a relatively minor ...
Cooke, C.A., Lydia C. Green, Itaru Samejima, Flavia de Lima Alves, Farr, CJ, Samejima, I., Earnshaw, W.C., Samejima, K., Vagnarelli, P., Kelly, D.A., Kerr, A., David A. Kelly, Hudson, DF, Hudson, D.F., Carol A. Cooke, Kerr, A, Vargiu, G., Cooke, CA, Giulia Vargiu, Hiromi Ogawa, Green, LC, Alves, FDL, Damien F. Hudson, Ogawa, H, de Lima Alves, F, Ogawa, H., Alves, F.L., Green, L.C., Vagnarelli, P, Kumiko Samejima, Ohta, S, Alastair Kerr, Christine J. Farr, Shinya Ohta, William C. Earnshaw, Vargiu, G, Ohta, S., Farr, C.J., Paola Vagnarelli, Juri Rappsilber, Rappsilber, J., Samejima, I, Kelly, DA, Rappsilber, J, Samejima, K, Earnshaw, WC   +45 more
core   +1 more source

Condensin positioning at telomeres by shelterin proteins drives sister-telomere disjunction in anaphase

eLife, 2023
The localization of condensin along chromosomes is crucial for their accurate segregation in anaphase. Condensin is enriched at telomeres but how and for what purpose had remained elusive.
Léonard Colin, Celine Reyes, Julien Berthezene, Laetitia Maestroni, Laurent Modolo, Esther Toselli, Nicolas Chanard, Stephane Schaak, Olivier Cuvier, Yannick Gachet, Stephane Coulon, Pascal Bernard, Sylvie Tournier   +12 more
doaj   +1 more source

Molecular basis for SMC rod formation and its dissolution upon DNA binding. [PDF]

, 2015
SMC condensin complexes are central modulators of chromosome superstructure in all branches of life. Their SMC subunits form a long intramolecular coiled coil, which connects a constitutive "hinge" dimerization domain with an ATP-regulated "head ...
Soh, Young-Min, Stephan Gruber, Kim, Cheolhee, Kim, Y.-G., Kim, YG, Oh, B., Bürmann, F., Soh, Y., Shin, H.-C., Oh, Byung-Ha, Shin, HC, Lee, H., Durand-Diebold, M., Jin, KS, S. Gruber, Lee, Hansol, Kim, Ho Min, Shin, Ho-Chul, Kim, HM, Buermann, Frank, Toseland, C., Kim, H.M., Oda, T, Soh, YM, Durand-Diebold, Marie-Laure, -Diebold, ML, Kim, Y., Gruber, S., Jin, Kyeong Sik, Bürmann, Frank, Oh, BH, Durand-Diebold, M.-L., Kim, Yeon-Gil, Kong, Min-Seok, Kim, C, Oda, Takashi, C. Kim, Lee, Nam Ki, M-L Durand-Diebold, Lee, N.K., Kim, H., Kim, Soo Jin, Sato, M., Gruber, S, Toseland, Christopher P., Oda, T., Lee, NK, M-S Kong, Diebold-Durand, Marie-Laure, Lee, N., Y.-G. Kim, Kim, C., Toseland, C.P., Soh, Young Min, Kim, Ho-Min, Gruber, Stephan, Soh, Y.-M., Oh, B.-H., Sato, Mamoru, Buermann, F., Kim, S., Jin, K.S., Shin, H., Kim, S.J., Kong, M.-S., Kong, M., S. J. Kim, Burmann, F, Jin, K., C. P. Toseland   +69 more
core   +1 more source

Both Chromosome Decondensation and Condensation Are Dependent on DNA Replication in C.elegans Embryos [PDF]

, 2015
During cell division, chromatin alternates between a condensed state to facilitate chromosome segregation and a decondensed form when DNA replicates.
Blow, J. Julian; id_orcid, Karim Labib, Craig, Gillian, Remi Sonneville, Labib, Karim, Sonneville, Remi, Gillian Craig, Anton Gartner, J. Julian Blow, Blow, J. Julian, Labib, Karim; id_orcid, Gartner, Anton   +11 more
core   +1 more source