Results 11 to 20 of about 7,152 (199)
Levels of Ycg1 Limit Condensin Function during the Cell Cycle. [PDF]
PLoS Genetics, 2016 During mitosis chromosomes are condensed to facilitate their segregation, through a process mediated by the condensin complex. Although several factors that promote maximal condensin activity during mitosis have been identified, the mechanisms that ...
Tyler W Doughty +2 more
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Genome Biology, 2020 Background Structural maintenance of chromosomes (SMC) complexes are central organizers of chromatin architecture throughout the cell cycle. The SMC family member condensin is best known for establishing long-range chromatin interactions in mitosis ...
Yasutaka Kakui +7 more
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A role for condensin in mediating transcriptional adaptation to environmental stimuli
Life Science Alliance, 2021 Fast conditional depletion of the chromosomal condensin complex from budding yeast cells reveals roles in transcriptional regulation, especially during the establishment of new gene expression patterns.
Lucy Lancaster +3 more
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Condensin Regulates the Stiffness of Vertebrate Centromeres [PDF]
Molecular Biology of the Cell, 2009 When chromosomes are aligned and bioriented at metaphase, the elastic stretch of centromeric chromatin opposes pulling forces exerted on sister kinetochores by the mitotic spindle. Here we show that condensin ATPase activity is an important regulator of centromere stiffness and function.
Ribeiro, S.A. +10 more
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Evolutionary Patterns of the Genes Involved in the Integrity and Segregation of Chromosomes in Sawflies (Hymenoptera: Symphyta). [PDF]
Ecol EvolThis study identifies and characterizes the genes encoding cohesin and condensin complexes across Symphytan superfamilies, revealing their structural and functional roles with conserved motifs in maintaining genome stability. Phylogenetic analyses indicate that SMC genes originated from ancient duplication events, with notable gene loss (e.g., CAPG2 ...
Nalça AR, Korkmaz EM.
europepmc +2 more sources
Functional dissection of the Drosophila melanogaster condensin subunit Cap-G reveals its exclusive association with condensin I. [PDF]
PLoS Genetics, 2013 The heteropentameric condensin complexes have been shown to participate in mitotic chromosome condensation and to be required for unperturbed chromatid segregation in nuclear divisions.
Sabine Herzog +5 more
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Condensin action and compaction [PDF]
Current Genetics, 2018 Condensin is a multi-subunit protein complex that belongs to the family of structural maintenance of chromosomes (SMC) complexes. Condensins regulate chromosome structure in a wide range of processes including chromosome segregation, gene regulation, DNA repair and recombination.
Matthew Robert Paul +2 more
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An SMC-like protein binds and regulates Caenorhabditis elegans condensins. [PDF]
PLoS Genetics, 2017 Structural Maintenance of Chromosomes (SMC) family proteins participate in multisubunit complexes that govern chromosome structure and dynamics.
Lucy Fang-I Chao +4 more
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Condensins under the microscope [PDF]
Journal of Cell Biology, 2018 Condensins are key players in mitotic chromosome condensation. Using an elegant combination of state-of-the-art imaging techniques, Walther et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201801048) counted the number of Condensins, examined their behaviors on human mitotic chromosomes, and integrated the quantitative data to propose a new ...
Kazuhiro Maeshima +2 more
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Roles for Condensin in C. elegans Chromosome Dynamics. [PDF]
, 2011 Condensin complexes are essential for higher order organization of chromosome structure. Higher eukaryotes have two condensins (condensin I and II) dedicated to mitotic and meiotic chromosome dynamics. C. elegans was thought to be an anomaly, with only a
Collette, Karishma S.
core +5 more sources