Results 41 to 50 of about 7,152 (199)
Phospho-regulation of the Shugoshin - Condensin interaction at the centromere in budding yeast.
PLoS Genetics, 2020 Correct bioriented attachment of sister chromatids to the mitotic spindle is essential for chromosome segregation. In budding yeast, the conserved protein shugoshin (Sgo1) contributes to biorientation by recruiting the protein phosphatase PP2A-Rts1 and ...
Galal Yahya +7 more
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Condensin ATPase motifs contribute differentially to the maintenance of chromosome morphology and genome stability. [PDF]
PLoS Biology, 2018 Effective transfer of genetic information during cell division requires a major reorganization of chromosome structure. This process is triggered by condensin, a conserved pentameric ATPase essential for chromosome condensation.
Roger Palou +5 more
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Condensin goes with the family but not with the flow [PDF]
Genome Biology, 2008 Condensin and cohesin are loaded onto yeast chromosomes by a common mechanism at RNA polymerase III transcribed genes. Whereas cohesin translocates from these loading sites to mediate cohesion at secondary locations, condensin remains, bringing distant sites together into clusters.
Gartenberg, MR, Merkenschlager, M
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Condensin I recruitment to base damage-enriched DNA lesions is modulated by PARP1.
PLoS ONE, 2011 Condensin I is important for chromosome organization and segregation in mitosis. We previously showed that condensin I also interacts with PARP1 in response to DNA damage and plays a role in single-strand break repair.
Xiangduo Kong +6 more
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MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface
eLife, 2021 Dramatic change in chromosomal DNA morphology between interphase and mitosis is a defining features of the eukaryotic cell cycle. Two types of enzymes, namely cohesin and condensin confer the topology of chromosomal DNA by extruding DNA loops.
Martin Houlard +9 more
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Condensins: Organizing and Segregating the Genome [PDF]
Current Biology, 2005 Condensins are multi-subunit protein complexes that play a central role in mitotic chromosome assembly and segregation. The complexes contain 'structural maintenance of chromosomes' (SMC) ATPase subunits, and induce DNA supercoiling and looping in an ATP-hydrolysis-dependent manner in vitro.
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Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes [PDF]
Journal of Cell Science, 2007 The assembly of mitotic chromosomes is controlled by condensin complexes. In vertebrates, condensin I binds to chromatin in prometaphase, confers rigidity to chromosomes and enables the release of cohesin complexes from chromosome arms, whereas condensin II associates with chromosomes in prophase and promotes their condensation.
Lipp, J. +3 more
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Condensin DC loads and spreads from recruitment sites to create loop-anchored TADs in C. elegans
eLife, 2022 Condensins are molecular motors that compact DNA via linear translocation. In Caenorhabditis elegans, the X-chromosome harbors a specialized condensin that participates in dosage compensation (DC).
Jun Kim +9 more
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The loading of condensin in the context of chromatin
Current Genetics, 2016 The packaging of DNA into chromosomes is a ubiquitous process that enables living organisms to structure and transmit their genome accurately through cell divisions. In the three kingdoms of life, the architecture and dynamics of chromosomes rely upon ring-shaped SMC (Structural Maintenance of Chromosomes) condensin complexes.
Robellet, Xavier +2 more
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Nucleus, 2019 Plants possess the structural maintenance of chromosome (SMC) protein complexes cohesin, condensin, and SMC5/6, which function in fundamental biological processes such as sister chromatid cohesion, chromosome condensation and segregation, and damaged DNA
Takuya Sakamoto +3 more
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