Results 71 to 80 of about 6,249 (200)

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

eLife, 2018
Condensins are genome organisers that shape chromosomes and promote their accurate transmission. Several studies have also implicated condensins in gene expression, although any mechanisms have remained enigmatic. Here, we report on the role of condensin
Clémence Hocquet, Xavier Robellet, Laurent Modolo, Xi-Ming Sun, Claire Burny, Sara Cuylen-Haering, Esther Toselli, Sandra Clauder-Münster, Lars Steinmetz, Christian H Haering, Samuel Marguerat, Pascal Bernard   +11 more
doaj   +1 more source

Generative Cell Division, but Not Early Nuclear Reorganization, Requires Transcriptional Reactivation During Pollen Tube Growth

Plant Direct, Volume 10, Issue 6, June 2026.
ABSTRACT Bicellular pollen often enters a desiccated state wherein development is temporarily arrested, enabling long‐term survival while maintaining the capacity for rapid activation upon hydration. Although the generative cell in mature pollen of Lilium species is known to have completed DNA replication, its precise cell‐cycle status and the ...
Mio K. Shibuta, Aina Komatsu, Tsugumi Aso   +2 more
wiley   +1 more source

Cti1/C1D interacts with condensin SMC hinge and supports the DNA repair function of condensin [PDF]

Proceedings of the National Academy of Sciences, 2004
Condensin is a conserved five-subunit complex containing two SMC (structural maintenance of chromosomes) and three non-SMC subunits and plays a major role in mitotic chromosome condensation. Condensin also acts in interphase and is required for DNA repair and replication checkpoint control. We attempted to study the function of the condensin in greater
Ee Sin, Chen, Takashi, Sutani, Mitsuhiro, Yanagida   +2 more
openaire   +2 more sources

Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Minimal bacterial cells such as JCVI‐Syn3A provide a powerful system for uncovering the essential mechanisms of chromosome organization and segregation. Lacking canonical systems such as Min and ParABS, JCVI‐Syn3A relies primarily on structural maintenance of chromosomes (SMC) protein complexes for partitioning.
Andrew K. Maytin, Benjamin R. Gilbert, Zaida Luthey‐Schulten   +2 more
wiley   +1 more source

Condensin I folds the Caenorhabditis elegans genome.

The structural maintenance of chromosome (SMC) complexes-cohesin and condensins-are crucial for chromosome separation and compaction during cell division. During the interphase, mammalian cohesins additionally fold the genome into loops and domains. Here
Haemmerli, Anja, Gitchev, Todor, Campos, Julie, Ewald, Collin Y, Mozziconacci, Julien, Semple, Jennifer I., Volodkina, Valeriia, Annan, Ahrmad, Meister, Peter, Dakhovnik, Oleksandr; id_orcid, Statzer, Cyril, Das, Moushumi, Ewald, Collin; id_orcid, Dakhovnik, Alexander, Scotton, Janik, Semple, Jennifer I   +15 more
core   +2 more sources

Condensin function in dosage compensation [PDF]

Epigenetics, 2009
Dosage compensation is an essential process that equalizes X-linked gene dosage between the sexes. In the worm Caenorhabditis elegans, a complex of proteins called the dosage compensation complex (DCC) binds both X chromosomes in hermaphrodites to downregulate gene expression two-fold and hence to reduce X-linked gene expression levels equal to that in
openaire   +2 more sources

Pitfalls and missing links in current understanding of 4D genomes

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley   +1 more source

Metaphase chromosome structure is dynamically maintained by condensin I-directed DNA (de)catenation

eLife, 2017
Mitotic chromosome assembly remains a big mystery in biology. Condensin complexes are pivotal for chromosome architecture yet how they shape mitotic chromatin remains unknown.
Ewa Piskadlo, Alexandra Tavares, Raquel A Oliveira   +2 more
doaj   +1 more source

Cell cycle regulation of condensin Smc4 [PDF]

Oncotarget, 2019
The condensin complex is a conserved ATPase which promotes the compaction of chromatin during mitosis in eukaryotic cells. Condensin complexes have in addition been reported to contribute to interphase processes including sister chromatid cohesion. It is not understood how condensins specifically become competent to facilitate chromosome condensation ...
Wei-Shan, Hsu, Amit, Vas C., Clarke, Duncan J.   +2 more
openaire   +2 more sources

Developmental expression of Ap‐Vas proteins in aphids and flies reveals their evolutionary roles in insects

Insect Molecular Biology, Volume 35, Issue 3, Page 217-231, June 2026.
Duplication of vas genes is universally observed in aphids, and phylogenetic analysis indicates that this event predates the divergence of Aphididae and Phylloxeridae. Ap‐vas1 is germline‐specific, whereas Ap‐vas2–4 exhibit somatic expression, indicating functional divergence during aphid embryogenesis.
Gee‐Way Lin, Szu‐Chieh Wang, Charles E. Cook, Ming‐Der Lin, Chun‐che Chang   +4 more
wiley   +1 more source