Results 71 to 80 of about 7,152 (199)
Cell cycle regulation of condensin Smc4 [PDF]
Oncotarget, 2019 The condensin complex is a conserved ATPase which promotes the compaction of chromatin during mitosis in eukaryotic cells. Condensin complexes have in addition been reported to contribute to interphase processes including sister chromatid cohesion. It is not understood how condensins specifically become competent to facilitate chromosome condensation ...
Wei-Shan, Hsu +2 more
openaire +2 more sources
Condensin-mediated remodeling of the mitotic chromatin landscape in fission yeast
, 2020 The eukaryotic genome consists of DNA molecules far longer than the cells that contain them. They reach their greatest compaction during chromosome condensation in mitosis. This process is aided by condensin, a structural maintenance of chromosomes (SMC)
David J Barry (8320179) +3 more
core
Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. [PDF]
PLoS Genetics, 2014 During development of the cerebral cortex, neural stem cells (NSCs) divide symmetrically to proliferate and asymmetrically to generate neurons. Although faithful segregation of mitotic chromosomes is critical for NSC divisions, its fundamental mechanism ...
Kenji Nishide, Tatsuya Hirano
doaj +1 more source
Glucose Transporter 1 in Health and Disease
MedComm, Volume 7, Issue 8, August 2026.As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai +3 more
wiley +1 more source
Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling [PDF]
Open Biology, 2015 SMC proteins are essential components of three protein complexes that are important for chromosome structure and function. The cohesin complex holds replicated sister chromatids together, whereas the condensin complex has an essential role in mitotic ...
Helena Barysz +6 more
doaj +1 more source
Molecular Ecology, Volume 35, Issue 16, August 2026.ABSTRACT Urbanization has become one of the leading causes of habitat transformation affecting ecosystem functioning. However, the transcriptomic response to urbanization remains poorly understood. Here, we conducted a transcriptomic analysis along an urbanization gradient under different warming temperatures.
Katarzyna Dudek, Guillaume Wos
wiley +1 more source
Factors Determining Sirtuin‐1 Target Engagement
Advanced Biology, Volume 10, Issue 7, July 2026.ABSTRACT Sirtuin‐1 (Sirt1) is a key NAD+‐dependent deacylase regulating metabolism, stress responses, genome stability, and aging. Although well‐characterized biochemically and structurally, its substrate selectivity remains unclear: in vitro, Sirt1 appears promiscuous, while in vivo it activates particular processes in response to different stimuli ...
Petra Neumann‐Staubitz +3 more
wiley +1 more source
Condensin confers the longitudinal rigidity of chromosomes [PDF]
Nature Cell Biology, 2015 In addition to inter-chromatid cohesion, mitotic and meiotic chromatids must have three physical properties: compaction into 'threads' roughly co-linear with their DNA sequence, intra-chromatid cohesion determining their rigidity, and a mechanism to promote sister chromatid disentanglement.
Martin Houlard +5 more
openaire +2 more sources
Real-time detection of single-molecule DNA compaction by condensin I
, 2004 BACKGROUND: Condensin is thought to contribute to large-scale DNA compaction during mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures DNA structure at a mechanistic level.
Terence R Strick +5 more
core +1 more source
Condensin I protects meiotic cohesin from WAPL-1 mediated removal.
PLoS Genetics, 2018 Condensin complexes are key determinants of higher-order chromatin structure and are required for mitotic and meiotic chromosome compaction and segregation.
Margarita R Hernandez +5 more
doaj +1 more source