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The interaction between KIF4A and condensin I.
, 2018 (A) HeLa cells expressing EGFP-KIF4A WT or S1186 were arrested at mitosis and the KIF4A-condensin I complex was recovered by immunoprecipitation against GFP and SMC2.
Kiichi Fukui (2036467) +3 more
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Cell Reports, 2017 How metazoan genomes are structured at the nanoscale in living cells and tissues remains unknown. Here, we adapted a quantitative FRET (Förster resonance energy transfer)-based fluorescence lifetime imaging microscopy (FLIM) approach to assay nanoscale ...
David Llères +5 more
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Control of chromosome interactions by condensin complexes
Current Opinion in Cell Biology, 2015 Although condensin protein complexes have long been known for their central role during the formation of mitotic chromosomes, new evidence suggests they also act as global regulators of genome topology during all phases of the cell cycle. By controlling intra-chromosomal and inter-chromosomal DNA interactions, condensins function in various contexts of
Frosi, Yuri, Haering, Christian H
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A transcription factor primes the condensin pump [PDF]
Journal of Cell Biology, 2018 Chromosome condensation is regulated by the condensin complex but whether this process is subject to transcriptional control is poorly understood. In this issue, Schiklenk et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201711097) reveal that the transcription factor Zas1 mediates timely chromosome condensation and promotes transcription of ...
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The role of condensin in chromosome resolution [PDF]
, 2012 The condensin complex is a key determinant of mitotic chromosome architecture. In addition to its role in mitotic chromosome compaction, condensin is required for resolution of sister chromatid linkages during chromosome segregation in anaphase.
Charbin, AA
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Scientific Reports, 2017 Condensin complexes play crucial roles in chromosome condensation that is a fundamental process to establish the “rod-like” shape of chromosome structure in mitosis.
Yuya Kagami +2 more
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Analysis of the interplay between condensin and chromatin [PDF]
, 2015 The multi-subunit condensin protein complex plays essential roles in the structural organization of eukaryotic genomes. Its function is particularly important for the maintenance of mitotic chromosome structure during their segregation into daughter ...
Frosi, Yuri
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, 2012 © 2012 Dr. Lydia Crystal GreenThe condensins are essential protein complexes that are required for correct organisation and division of chromosomes during mitosis. Two condensin complexes exist in higher eukaryotes, condensin I and condensin II.
Green, Lydia Crystal
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, 2013 © 2013 Dr. Ji Hun KimPublications included in thesis:Kim, J. H., Zhang, T., Wong, N. C., Davidson, N., Maksimovic, J., Oshlack, A., et al. (2013). Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes.
Kim, Ji Hun
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Condensin IDC, DPY-21, and CEC-4 maintain X chromosome repression in C. elegans.
PLoS GeneticsDosage compensation in Caenorhabditis elegans equalizes X-linked gene expression between XX hermaphrodites and XO males. The process depends on a condensin-containing dosage compensation complex (DCC), which binds the X chromosomes in hermaphrodites to ...
Jessica Trombley +4 more
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