Results 101 to 110 of about 7,152 (199)
Biology Open, 2017 After mitosis, nuclear reorganization occurs together with decondensation of mitotic chromosomes and reformation of the nuclear envelope, thereby restoring the Ran-GTP gradient between the nucleus and cytoplasm.
Keita Aoki, Hironori Niki
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, 1999 Xenopus 13S condensin converts interphase chromatin into mitotic-like chromosomes, and, in the presence of ATP and a type I topoisomerase, introduces (+) supercoils into DNA. The specific production of (+) trefoil knots in the presence of condensin and a
Cozzarelli, N. R. +4 more
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The spatial segregation of pericentric cohesin and condensin in the mitotic spindle [PDF]
, 2013 The mitotic chromatin spring is organized into a rosette of intramolecular loops of pericentric chromatin by condensin and cohesin. Model convolution reveals that condensin clusters along the spindle axis, while cohesin is dispersed radially along ...
Haase, Julian +5 more
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Establishment of dsDNA-dsDNA interactions by the condensin complex. Tang et al
, 2023 SDS-PAGE Coomassie staining and fluorescence scanning of condensin purification fractions. Condensin loading assays using either condensin immunoprecipitation or DNA immunoprecipitation.THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Tang, M (via Mendeley Data) +1 more
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Cell Reports, 2017 How metazoan genomes are structured at the nanoscale in living cells and tissues remains unknown. Here, we adapted a quantitative FRET (Förster resonance energy transfer)-based fluorescence lifetime imaging microscopy (FLIM) approach to assay nanoscale ...
David Llères +5 more
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Condensin I folds the Caenorhabditis elegans genome. [PDF]
The structural maintenance of chromosome (SMC) complexes-cohesin and condensins-are crucial for chromosome separation and compaction during cell division. During the interphase, mammalian cohesins additionally fold the genome into loops and domains. Here
Haemmerli, Anja +15 more
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Control of chromosome interactions by condensin complexes
Current Opinion in Cell Biology, 2015 Although condensin protein complexes have long been known for their central role during the formation of mitotic chromosomes, new evidence suggests they also act as global regulators of genome topology during all phases of the cell cycle. By controlling intra-chromosomal and inter-chromosomal DNA interactions, condensins function in various contexts of
Frosi, Yuri, Haering, Christian H
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The condensin ATPase: towards a mechanistic view of chromosome condensation [PDF]
, 2014 The central aim of cell division is the accurate transmission of replicated genetic material to daughter cells. To enable this segregation, centimetre-long DNA molecules must be organised into condensed micrometre-sized chromosomes.
Thadani, RR
core
Condensin II interacts with BLM helicase in S phase to maintain genome stability
Communications BiologyVertebrates possess two condensins, I and II, that are essential for chromosome condensation and segregation. Condensin II has also been implicated in maintaining genome integrity outside of mitosis, though the underlying mechanisms are unclear. Here, we
Brian Rodemoyer +3 more
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Condensin-dependent chromatin condensation represses transcription globally during quiescence
, 2018 SUMMARYQuiescence is a stress-resistant state in which cells reversibly exit the mitotic cell cycle and suspend most cellular processes. Quiescence is essential for stem cell maintenance and its misregulation is implicated in tumor formation.
Seungsoo Kim +9 more
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