Results 101 to 110 of about 6,249 (200)
Tumour Cell Size Control and Its Impact on Tumour Cell Function
Cell Proliferation, Volume 58, Issue 12, December 2025.The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley +1 more source
Chromosome Territories Meet a Condensin
PLoS Genetics, 2012 In human diploid cells, 23 pairs of chromosomes become recognizable as a discrete set of rod-shaped entities during the mitotic stage of the cell cycle. Upon exit from mitosis, they decondense and are packed together into the nucleus, in which individual chromosomes are no longer discernible.
openaire +4 more sources
New Phytologist, Volume 248, Issue 6, Page 2833-2849, December 2025.Summary Target of rapamycin (TOR) kinase is the hub of a eukaryotic master signaling network that integrates nutritional and hormonal signals into cellular activities. Most studies on TOR in plants have focused on seedlings, where TOR is most responsive to light and sucrose.
Brendan M. O'Leary +5 more
wiley +1 more source
The role of condensin in chromosome resolution [PDF]
, 2012 The condensin complex is a key determinant of mitotic chromosome architecture. In addition to its role in mitotic chromosome compaction, condensin is required for resolution of sister chromatid linkages during chromosome segregation in anaphase.
Charbin, AA
core
Cell Reports, 2017 How metazoan genomes are structured at the nanoscale in living cells and tissues remains unknown. Here, we adapted a quantitative FRET (Förster resonance energy transfer)-based fluorescence lifetime imaging microscopy (FLIM) approach to assay nanoscale ...
David Llères +5 more
doaj +1 more source
, 2013 © 2013 Dr. Ji Hun KimPublications included in thesis:Kim, J. H., Zhang, T., Wong, N. C., Davidson, N., Maksimovic, J., Oshlack, A., et al. (2013). Condensin I associates with structural and gene regulatory regions in vertebrate chromosomes.
Kim, Ji Hun
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Control of chromosome interactions by condensin complexes
Current Opinion in Cell Biology, 2015 Although condensin protein complexes have long been known for their central role during the formation of mitotic chromosomes, new evidence suggests they also act as global regulators of genome topology during all phases of the cell cycle. By controlling intra-chromosomal and inter-chromosomal DNA interactions, condensins function in various contexts of
Frosi, Yuri, Haering, Christian H
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Scientific Reports, 2017 Condensin complexes play crucial roles in chromosome condensation that is a fundamental process to establish the “rod-like” shape of chromosome structure in mitosis.
Yuya Kagami +2 more
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Analysis of the interplay between condensin and chromatin
, 2015 The multi-subunit condensin protein complex plays essential roles in the structural organization of eukaryotic genomes. Its function is particularly important for the maintenance of mitotic chromosome structure during their segregation into daughter ...
Frosi, Yuri
core +1 more source
Molecular and Genetic Analysis of Condensin Function in Vertebrate Cells [PDF]
, 2008 We engineered mutants into residues of SMC2 to dissect the role of ATPase function in the condensin complex. These residues are predicted to be involved in ATP binding or hydrolysis and in the Q-loop, which is thought to act as a mediator of ...
Hudson, D.F. +11 more
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