Results 121 to 130 of about 6,249 (200)

The condensin ATPase: towards a mechanistic view of chromosome condensation [PDF]

, 2014
The central aim of cell division is the accurate transmission of replicated genetic material to daughter cells. To enable this segregation, centimetre-long DNA molecules must be organised into condensed micrometre-sized chromosomes.
Thadani, RR
core  

A transcription factor primes the condensin pump

, 2018
Chromosome condensation is regulated by the condensin complex but whether this process is subject to transcriptional control is poorly understood. In this issue, Schiklenk et al. (2018. J. Cell Biol. https://doi.org/10.1083/jcb.201711097) reveal that the
Jennifer L. Gerton
core   +1 more source

Understanding the role of condensin II in chromosome structure

, 2015
© 2015 Dr. Muhammed Adnan M. BakhrebahThe condensin complex plays a key role in organising mitotic chromosomes. In vertebrates, there are two condensin complexes that have independent and cooperative roles in folding mitotic chromosomes.
Bakhrebah, Muhammed Adnan M.
core  

Different roles for Aurora B in condensin targeting during mitosis and meiosis

, 2011
Condensin complexes are essential for mitotic and meiotic chromosome segregation. Caenorhabditis elegans, like other metazoans, has two distinct mitotic and meiotic condensin complexes (I and II), which occupy distinct chromosomal domains and perform non-
Karishma S. Collette, Joshua N. Bembenek, Netta Golenberg, Gyorgyi Csankovszki, Emily L. Petty   +4 more
core   +1 more source

Condensin-mediated restriction of retrotransposable elements facilitates brain development in Drosophila melanogaster

Nature Communications
Neural stem and progenitor cell (NSPC) maintenance is essential for ensuring that organisms are born with proper brain volumes and head sizes. Microcephaly is a disorder in which babies are born with significantly smaller head sizes and cortical volumes.
Bert I. Crawford, Mary Jo Talley, Joshua Russman, James Riddle, Sabrina Torres, Troy Williams, Michelle S. Longworth   +6 more
doaj   +1 more source

New insights into the role of condensin in Saccharomyces cerevisiae

, 2018
Structural Maintenance of Chromosomes (SMC) complexes are highly conserved from prokaryotes to eukaryotes. Saccharomyces cerevisiae has six SMC proteins which form three SMC-complexes in association with non-SMC subunits namely, the cohesin complex, the ...
Lakshmi, Mahendrawada R
core  

Condensin IDC has a functional ATPase that is required for X-Chromosome dosage compensation in C. elegans. [PDF]

Genetics
Chawla B, Jatia S, Sloan D, Eduful J, Mendoza H, McClear CA, Tran J, Csankovszki G.   +7 more
europepmc   +1 more source

Regulation of Chromosome Condensation by Intrinsically Disordered Regions in Condensin

Faithful transmission of the genome during mitosis is an irreversible event that determines the survival and propagation of all living organisms. A prerequisite for this process is the large-scale restructuring of amorphous chromatin into distinct, rod ...
Pastic, Alyssa
core   +1 more source

A developmental condensin I complex assists the Paramecium PiggyMac domesticated transposase during programmed DNA elimination. [PDF]

Nucleic Acids Res
Balan T, Bazin-Gélis M, Guérineau M, Vitali V, Zangarelli C, Arnaiz O, Abbou L, Altair A, Boutte du Jonchay A, Camprodon A, Giovannetti M, Poitrenaud C, Schumacher E, Bischerour J, Tassin AM, Régnier V, Chevreux G, Duharcourt S, Bétermier M.   +18 more
europepmc   +1 more source

Condensin accelerates long-range intra-chromosomal interactions. [PDF]

Nat Commun
Zou F, Li Y, Földes T, Pinholt HD, Smith C, Mirny L, Bai L.   +6 more
europepmc   +1 more source