Results 61 to 70 of about 10,706 (194)

The expanding territories of condensin II [PDF]

Cell Cycle, 2015
The 3D structure of the eukaryotic genome and its spatial regulation within nuclei are governed by a range of architectural proteins. One class of such factors is the condensins, highly conserved multi-subunit protein complexes. Most eukaryotic species have 2 condensins, condensin I and II, and both condensins are essential for mitotic chromosome ...
Yoko Ito, Masashi Narita
openaire   +3 more sources

TFIIIC Localizes Budding Yeast ETC Sites to the Nuclear Periphery [PDF]

, 2012
Peer reviewedPublisher ...
Botsios, Sotirios, Donaldson, Anne Dunlop, Donze, David, Hiraga, Shinichiro   +3 more
core   +2 more sources

Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts. [PDF]

, 2005
During cell division, condensation and resolution of chromosome arms and the assembly of a functional kinetochore at the centromere of each sister chromatid are essential steps for accurate segregation of the genome by the mitotic spindle, yet the ...
Freedman, Benjamin S, Heald, Rebecca, Maresca, Thomas J   +2 more
core   +2 more sources

How to halve ploidy : lessons from budding yeast meiosis [PDF]

, 2012
Maintenance of ploidy in sexually reproducing organisms requires a specialized form of cell division called meiosis that generates genetically diverse haploid gametes from diploid germ cells.
Arumugam, Prakash, Kerr, Gary W., Sarkar, Sourav   +2 more
core   +1 more source

Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. [PDF]

PLoS Genetics, 2014
During development of the cerebral cortex, neural stem cells (NSCs) divide symmetrically to proliferate and asymmetrically to generate neurons. Although faithful segregation of mitotic chromosomes is critical for NSC divisions, its fundamental mechanism ...
Kenji Nishide, Tatsuya Hirano
doaj   +1 more source

Determining cellular CTCF and cohesin abundances to constrain 3D genome models. [PDF]

, 2019
Achieving a quantitative and predictive understanding of 3D genome architecture remains a major challenge, as it requires quantitative measurements of the key proteins involved.
Cattoglio, Claudia, Dailey, Gina M, Darzacq, Xavier, Ellenberg, Jan, Hansen, Anders S, Hantsche-Grininger, Merle, Ho, Jaclyn J, Hossain, M Julius, Inouye, Carla J, Pustova, Iryna, Tjian, Robert, Walther, Nike   +11 more
core   +2 more sources

Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu, Zexin Zhu, Lauren Fields, Hua Zhang, Lingjun Li   +4 more
wiley   +1 more source

Significance of stereologically spatiotemporal cells in molecular medicine

Clinical and Translational Medicine, Volume 15, Issue 9, September 2025.
Abstract Spatiotemporal distributions of intracellular elements (e.g., small molecules, proteins and organelles) dynamically altered in response to extracellular stimuli and pathogens, regulating those element movements, remodelling, and functions independently of mere changes in element abundance.
Xuanqi Liu, Wanxin Duan, Yuyang Qiu, Ruyi Li, Yuanlin Song, Xiangdong Wang   +5 more
wiley   +2 more sources

Condensin controls cellular RNA levels through the accurate segregation of chromosomes instead of directly regulating transcription

eLife, 2018
Condensins are genome organisers that shape chromosomes and promote their accurate transmission. Several studies have also implicated condensins in gene expression, although any mechanisms have remained enigmatic. Here, we report on the role of condensin
Clémence Hocquet, Xavier Robellet, Laurent Modolo, Xi-Ming Sun, Claire Burny, Sara Cuylen-Haering, Esther Toselli, Sandra Clauder-Münster, Lars Steinmetz, Christian H Haering, Samuel Marguerat, Pascal Bernard   +11 more
doaj   +1 more source

Are SMC complexes loop extruding factors? Linking theory with fact [PDF]

, 2019
The extreme length of chromosomal DNA requires organizing mechanisms to both promote functional genetic interactions and ensure faithful chromosome segregation when cells divide.
Akai, Alipour, Alt, Anderson, Badrinarayanan, Beckouët, Brackley, Brackley, Busslinger, Bürmann, Davidson, Diebold-Durand, Dixon, Eeftens, Fennell-Fezzie, Fudenberg, Ganji, Gerlich, Gibcus, Gligoris, Goloborodko, Goloborodko, Gruber, Guacci, Haarhuis, Hadjur, Haering, Hirano, Hirano, Hopfner, Hornig, Houlard, Hu, Kamada, Kanke, Kimura, Kimura, Kimura, Kinoshita, Kojic, Kschonsak, Lavoie, Lengronne, Li, Lipp, Marko, Minnen, Mizuguchi, Murayama, Murayama, Murayama, Nasmyth, Nasmyth, Naumova, Nora, Ono, Ono, Parelho, Paulson, Petela, Piazza, Racko, Rao, Rao, Robellet, Rojowska, Rolef Ben-Shahar, Rowland, Saitoh, Saka, Sanborn, Schalbetter, Schleiffer, Schwarzer, Sexton, Shintomi, Shintomi, Srinivasan, St-Pierre, Stigler, Strunnikov, Sullivan, Sutani, Tada, Terakawa, Uhlmann, Uhlmann, Uhlmann, Unal, Vian, Walther, Wang, Wang, Wang, Wells, Wendt, Wutz, Yamamoto, Yoshimura, Zabrady, Zawadzka, Çamdere, Çamdere   +102 more
core   +1 more source