Results 91 to 100 of about 267,969 (148)

CONE SNAIL BIOLOGY, BIOPROSPECTING AND CONSERVATION [PDF]

, 2013
International audienceCone snails are predatory marine gastropods that prey on worms, molluscs and fish. The venoms of these animals are true pharmacological treasures, and with the recent approval of the first cone snail venom-derived drug, the pressure
Dutertre, Sébastien, Lewis, Richard,
core   +1 more source

ω-Conotoxins GVIA, MVIIA and CVID: SAR and Clinical Potential

Marine Drugs, 2006
: Highly selective N-type voltage-gated calcium (CaV) channel inhibitors from cone snail venom (the ω-conotoxins) have emerged as a new class of therapeutics for the treatment of chronic and neuropathic pain.
Richard J. Lewis, Christina I. Schroeder
doaj   +1 more source

Dramatic intraspecimen variations within the injected venom of Conus consors: An unsuspected contribution to venom diversity

, 2010
International audienceWith the advent of highly sensitive mass spectrometry techniques, the minute amount of various secretions produced by living animals can be studied to a level of details never attained before.
Favreau, Philippe, Stocklin, Reto, Biass, Daniel, Dutertre, Sebastien   +3 more
core   +1 more source

Conopeptide production through biosustainable snail farming [PDF]

, 2012
An area of intensive focus and research has been in the study of conopeptides isolated from cone snail venom. These complex peptide venoms contain between 50 and 100 different bioactive substances, many of which can be utilized for a variety of ...
Milisen, Jeffrey William
core   +1 more source

Cone snail prolyl-4-hydroxylase alpha-subunit sequences derived from transcriptomic data and mass spectrometric analysis of variable proline hydroxylation in C. amadis venom

, 2019
Putative prolyl-4-hydroxylase (P4H) alpha-subunit sequences have been extracted by mining transcriptomic data obtained from seven cone snail species C. amadis, C. monile, C. araneosus, C. miles, C. litteratus, C. frigidus, and C. ebraeus.
Vijayasarathy, M., Balaram, P., Balaram, P, Vijayasarathy, M   +3 more
core   +1 more source

Histopathological analysis and in situ localisation of Australian tiger snake venom in two clinically envenomed domestic animals [PDF]

, 2011
Objective: To assess histopathological changes in clinically envenomed tiger snake patients and identify tissue specific localisation of venom toxins using immunohistochemistry.
Jacoby-Alner, T.E., Davern, K.M., Swindells, K., Stephens, N., Balmer, L., Brown, S.G.A.   +5 more
core  

Conodipine-P1-3, the First Phospholipases A₂ Characterized from Injected Cone Snail Venom. [PDF]

Mol Cell Proteomics, 2019
Möller C, Davis WC, Clark E, DeCaprio A, Marí F.   +4 more
europepmc   +1 more source

Cone snail venom-inspired somatostatin receptor 4 (SSTR₄) agonists as new drug leads for peripheral pain. [PDF]

Sci Rep
Bjørn-Yoshimoto WE, Ramiro IBL, Koch TL, Engholm E, Yeung HY, Sørensen KK, Goddard CM, Jensen KL, Smith NA, Martin LF, Smith BJ, Madsen KL, Jensen KJ, Patwardhan A, Safavi-Hemami H.   +14 more
europepmc   +1 more source

Activation of CiD Interneurons in Zebrafish by the Venom of the Fish Hunting Cone Snail Conus catus

, 2011
The neuroexcitatory peptide in the venom of the fish-hunting cone snail Conus catus causes rapid tetanic paralysis in its prey. The pathway through which this response is propagated is unknown.
Edmund, Erika
core  

Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom. [PDF]

J Proteomics, 2015
Robinson SD, Safavi-Hemami H, Raghuraman S, Imperial JS, Papenfuss AT, Teichert RW, Purcell AW, Olivera BM, Norton RS.   +8 more
europepmc   +1 more source