Results 91 to 100 of about 5,046 (227)

Bioactive Mimetics of Conotoxins and other Venom Peptides

Toxins, 2015
Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intrathecal mode
Peter J. Duggan, Kellie L. Tuck
doaj   +1 more source

Highlight: Prey-Determined Patterns in Cone Snail Venom Evolution [PDF]

Mol Biol Evol
europepmc   +2 more sources

Molecular Phylogeny, Classification and Evolution of Conopeptides [PDF]

, 2018
Conopeptides are toxins expressed in the venom duct of cone snails (Conoidea, Conus). These are mostly well-structured peptides and mini-proteins with high potency and selectivity for a broad range of cellular targets.
Favreau, P., Koua, D., Olivera, B., Puillandre, N., Stöcklin, R.   +4 more
core  

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Efficient oxidative folding of conotoxins and the radiation of venomous cone snails [PDF]

Proceedings of the National Academy of Sciences, 2003
The 500 different species of venomous cone snails (genus Conus ) use small, highly structured peptides (conotoxins) for interacting with prey, predators, and competitors. These peptides are produced by translating mRNA from many genes belonging to only a few gene superfamilies.
Grzegorz, Bulaj, Olga, Buczek, Ian, Goodsell, Elsie C, Jimenez, Jessica, Kranski, Jacob S, Nielsen, James E, Garrett, Baldomero M, Olivera   +7 more
openaire   +2 more sources

Identification and Characterization of a Novel Family of Cysteine-Rich Peptides (MgCRP-I) from Mytilus galloprovincialis [PDF]

, 2015
We report the identification of a novel gene family (named MgCRP-I) encoding short secreted cysteine-rich peptides in the Mediterranean mussel Mytilus galloprovincialis.
Benincasa, Monica, Gerdol, Marco, Giulianini, Piero Giulio, Guarnaccia, Corrado, Lucaf\uf2, Marianna, Manfrin, Chiara, Moro, Gianluca De, Pallavicini, Alberto, Puillandre, Nicolas, Sava, Gianni, Torboli, Valentina, Venier, Paola, Zlatev, Ventislav   +12 more
core   +2 more sources

Advances in Bioinspired Interfacial Adhesion with Frictional Enhancement: From Fundamental Research to Biomimetic Applications

Small Structures, Volume 7, Issue 2, February 2026.
Biological models in nature reveal remarkable friction‐adhesion mechanisms, driven by intermolecular forces and suction. Researchers leverage these principles to design advanced materials with enhanced adhesion properties. By optimizing these materials under stimuli like light and electricity, new solutions emerge for regulating interface interactions ...
Yunfang Sun, Xuemin Yang, Guang Liu, Liwen Zhang, Yue Fu, Ping Li, Weiteng Li, Guang Yang, Huanyu Cheng, Huawei Chen   +9 more
wiley   +1 more source

Conus vexillum venom induces oxidative stress in Ehrlich's ascites carcinoma cells: an insight into the mechanism of induction

Journal of Venomous Animals and Toxins including Tropical Diseases, 2013
Background It is estimated that venoms of marine cone snails (genus Conus) contain more than 100,000 different small peptides with a wide range of pharmacological and biological actions.
Mohamed A Abdel-Rahman, Ismail M Abdel-Nabi, Mohamed S El-Naggar, Osama A Abbas, Peter N Strong   +4 more
doaj   +1 more source

Novel conopeptides of largely unexplored Indo Pacific Conus sp. [PDF]

, 2016
Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds having a broad spectrum of ...
D'Souza, L., De Mot, R., Devi, P., Ghequire, M.G.K., Lebbe, E.K.M., Mille, B.G., Peigneur, S., Ravichandran, S., Tytgat, J., Waelkens, E.   +9 more
core  

Centipede venoms as a source of drug leads [PDF]

, 2016
peerreview_statement: The publishing and review policy for this title is described in its Aims & Scope. aims_and_scope_url: http://www.tandfonline.com/action/journalInformation?show=aimsScope&journalCode=iedc20© 2016 Taylor and Francis.
de la Vega RC, Eivind A.B. Undheim, Glenn F. King, King GF, Liu Z-C, Ronald A. Jenner, Smith JJ   +6 more
core   +1 more source