Results 111 to 120 of about 5,046 (227)
Asian Pacific Journal of Tropical Biomedicine, 2020 Objective: To determine the new M-superfamily conotoxins from molluscivorous snail Conus bandanus in Vietnam. Methods: Conus bandanus venom was fractionated and purified on HPLC system with an analytical reversed-phase C18 column in order to screen small
Nguyen Bao +2 more
doaj +1 more source
Beyond Conus: Phylogenetic relationships of Conidae based on complete mitochondrial genomes [PDF]
, 2017 Understanding how the extraordinary taxonomic and ecological diversity of cone snails (Caenogastropoda: Conidae) evolved requires a statistically robust phylogenetic framework, which thus far is not available. While recent molecular phylogenies have been
Puillandre, Nicolas +2 more
core +2 more sources
The Evolution of Fangs, Venom, and Mimicry Systems in Blenny Fishes [PDF]
, 2017 Venom systems have evolved on multiple occasions across the animal kingdom, and they can act as key adaptations to protect animals from predators. Consequently, venomous animals serve as models for a rich source of mimicry types, as non-venomous ...
Amanda Nouwens +23 more
core +6 more sources
Journal of Biogeography, Volume 52, Issue 10, October 2025.ABSTRACT Aim Genetic diversity and connectivity are crucial to informing the conservation strategy for deep‐sea organisms, especially those threatened by deep‐sea mining. The vent mussel Bathymodiolus septemdierum has an extraordinary trans‐oceanic distribution range across the Indo‐West Pacific including numerous sites eyed for exploitation.
Qin Mao +10 more
wiley +1 more source
Conotoxins: Therapeutic Potential and Application
Marine Drugs, 2006 The pharmacological variety of conotoxins, diverse peptides found in the venoms of marine cone snails, is well recognized. Venoms from each of the estimated 500 species of cone snails contain 50 to 200 distinct biologically active peptides.
Richard T. Layer, J. Michael McIntosh
doaj +1 more source
A Novel Hyaluronidase from Brown Spider (Loxosceles intermedia) Venom (Dietrich's Hyaluronidase): From Cloning to Functional Characterization [PDF]
, 2013 Loxoscelism is the designation given to clinical symptoms evoked by Loxosceles spider's bites. Clinical manifestations include skin necrosis with gravitational spreading and systemic disturbs. the venom contains several enzymatic toxins.
Chaim, Olga Meiri +9 more
core +4 more sources
Pain therapeutics from cone snail venoms: From Ziconotide to novel non-opioid pathways [PDF]
Journal of Proteomics, 2019 There have been numerous attempts to develop non-opioid drugs for severe pain, but the vast majority of these efforts have failed. A notable exception is Ziconotide (Prialt®), approved by the FDA in 2004. In this review, we summarize the present status of Ziconotide as a therapeutic drug and introduce a wider framework: the potential of venom peptides ...
Helena, Safavi-Hemami +2 more
openaire +2 more sources
Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails
Marine Drugs, 2018 Marine cone snails are a large family of gastropods that have evolved highly potent venoms for predation and defense. The cone snail venom has exceptional molecular diversity in neuropharmacologically active compounds, targeting a range of receptors, ion
Nikita Abraham, Richard J. Lewis
doaj +1 more source
Diversity of conotoxin gene superfamilies in the venomous snail, Conus victoriae. [PDF]
PLoS ONE, 2014 Animal venoms represent a vast library of bioactive peptides and proteins with proven potential, not only as research tools but also as drug leads and therapeutics.
Samuel D Robinson +5 more
doaj +1 more source
Conotoxins Targeting Nicotinic Acetylcholine Receptors: An Overview
Marine Drugs, 2014 Marine snails of the genus Conus are a large family of predatory gastropods with an unparalleled molecular diversity of pharmacologically active compounds in their venom.
Eline K. M. Lebbe +3 more
doaj +1 more source