Results 131 to 140 of about 1,336 (154)
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Ichthyotoxicity caused by marine cone snail venoms?
Toxicon, 2005Ten venoms from marine cone snails were tested for ichthyotoxic effects on zebra fish (Brachydanio rerio) when added to the water. Only two venoms, from Conus capitaneus and Conus episcopatus, produced lethal effects at high concentrations (50-300 microg/ml) within 20-90 min. No sedative or hypnotic symptoms were observed.
Dietrich, Mebs, Silke, Kauferstein
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Comparative analysis of proteases in the injected and dissected venom of cone snail species [PDF]
Toxicon, 2013 The venom of cone snails has been the subject of intense studies because it contains small neuroactive peptides of therapeutic value. However, much less is known about their larger proteins counterparts and their role in prey envenomation. Here, we analyzed the proteolytic enzymes in the injected venom of Conus purpurascens and Conus ermineus ...
Carolina Möller +2 more
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Venomous cone snails: molecular phylogeny and the generation of toxin diversity
Toxicon, 2001In order to investigate the generation of conotoxin diversity, delta-conotoxin sequences from nine Conus species were analyzed in the context of their phylogeny. Using a standard molecular marker, mitochondrial 16S RNA, we determined that the delta-conotoxins were derived from three distinct species clades based on the phylogenetic reconstruction of a ...
D J, Espiritu +5 more
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Venomic study on cone snails (Conus spp.) from South Africa
Toxicon, 2011From six Conus species (Conus coronatus, Conus lividus, Conus mozambicus f. lautus, Conus pictus, Conus sazanka, Conus tinianus) collected off the eastern coast of South Africa the venoms were analyzed using MALDI-TOF mass spectrometry. Between 56 and 151 molecular masses most in a range of 1000 to 2500 Da, were identified.
Kauferstein, S. +9 more
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Journal of Proteome Research, 2015
Marine cone snail venoms are highly complex mixtures of peptides and proteins. They have been studied in-depth over the past 3 decades, but the modus operandi of the venomous apparatus still remains unclear. Using the fish-hunting Conus consors as a model, we present an integrative venomics approach, based on new proteomic results from the venom gland ...
Frédérique Lisacek +2 more
exaly +4 more sources
Marine cone snail venoms are highly complex mixtures of peptides and proteins. They have been studied in-depth over the past 3 decades, but the modus operandi of the venomous apparatus still remains unclear. Using the fish-hunting Conus consors as a model, we present an integrative venomics approach, based on new proteomic results from the venom gland ...
Frédérique Lisacek +2 more
exaly +4 more sources
Ion Channel Toxins and Therapeutics: From Cone Snail Venoms to Ciguatera
Therapeutic Drug Monitoring, 2000Ion channels are intimately linked to all neurotransmission and neurotransmitter release processes, but in disease states often contribute adversely to disease pathology. The diversity and distribution of ion channel types and subtypes being uncovered through the use of molecular biology and toxin probes present an exciting opportunity for the ...
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Journal of Proteome Research, 2010
Cone snails of the genus Conus are predatory marine gastropods mainly found in the shallow waters of the tropics and warm temperate seas. To prey on other marine organisms including fish, cone snails have evolved complex venoms synthesized and delivered by a highly sophisticated venom apparatus.
Helena, Safavi-Hemami +3 more
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Cone snails of the genus Conus are predatory marine gastropods mainly found in the shallow waters of the tropics and warm temperate seas. To prey on other marine organisms including fish, cone snails have evolved complex venoms synthesized and delivered by a highly sophisticated venom apparatus.
Helena, Safavi-Hemami +3 more
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HYBRID ECMO AND CONE SNAIL VENOM POISONING
Journal of the American College of Cardiology, 2022Renato C. Ong +2 more
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Revising the Role of Defense and Predation in Cone Snail Venom Evolution
2016Venoms are widely employed by numerous animals across disparate lineages for predation and defense. Among them, the deadly carnivorous cone snails are reputed for the potency of their venoms comprising small neurotoxic peptides known as conotoxins. Though a majority of cone snails prey on worms, some species prey on fish and other mollusks despite ...
Prashanth, Jutty Rajan +2 more
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