Results 121 to 130 of about 5,046 (227)

A study on presence of bioactive compounds in snail Achantina fulica [PDF]

open access: yes, 2010
The bioactivity study of the crude extract as well as the pure compounds isolated by preparative TLC, of the snail were carried on bacteria, Escherichia coli PBR 322, Vibrio cholerae and cockroaches Periplanata americana.
Zodape, G. V.
core   +2 more sources

Curses or Cures: A Review of the Numerous Benefits Versus the Biosecurity Concerns of Conotoxin Research

open access: yesBiomedicines, 2020
Conotoxins form a diverse group of peptide toxins found in the venom of predatory marine cone snails. Decades of conotoxin research have provided numerous measurable scientific and societal benefits.
Walden E. Bjørn-Yoshimoto   +6 more
doaj   +1 more source

A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties [PDF]

open access: yes, 2015
Neurotensin receptors have been studied as molecular targets for the treatment of pain, schizophrenia, addiction, or cancer. Neurotensin (NT) and Contulakin-G, a glycopeptide isolated from a predatory cone snail Conus geographus, share a sequence ...
Aleksandra eWalewska   +10 more
core   +2 more sources

Three-Dimensional Structure of Conotoxin tx3a: A m-1 Branch Peptide of the M-Superfamily [PDF]

open access: yes, 2008
The M-superfamily, one of eight major conotoxin superfamilies found in the venom of the cone snail, contains a Cys framework with disulfide-linked loops labeled 1, 2, and 3 (- CC1C2C3CC-). M-superfamily conotoxins can be divided into the m-1, -2, -3 and -
McDougal, Owen M.   +3 more
core   +1 more source

Characterization of the First Conotoxin from Conus ateralbus, a Vermivorous Cone Snail from the Cabo Verde Archipelago

open access: yesMarine Drugs, 2019
Conus ateralbus is a cone snail endemic to the west side of the island of Sal, in the Cabo Verde Archipelago off West Africa. We describe the isolation and characterization of the first bioactive peptide from the venom of this species.
Jorge L. B. Neves   +10 more
doaj   +1 more source

The CAP protein superfamily: function in sterol export and fungal virulence [PDF]

open access: yes, 2017
CAP superfamily proteins, also known as sperm-coating proteins, are found in all kingdoms of life and have been implicated in a variety of physiological contexts, including immune defense in plants and mammals, sperm maturation and fertilization, fungal ...
Di Pietro, Antonio, Schneiter, Roger
core  

Alpha9 nicotinic acetylcholine receptors and the treatment of pain [PDF]

open access: yes, 2009
Chronic pain is a vexing worldwide problem that causes substantial disability and consumes significant medical resources. Although there are numerous analgesic medications, these work through a small set of molecular mechanisms.
Absalom, Nathan   +4 more
core   +1 more source

Exploring Use of a Protein Cage System for Producing Bioactive Peptides in Escherichia coli

open access: yesMicrobial Biotechnology, Volume 18, Issue 6, June 2025.
Bioactive peptides can be difficult to manufacture biosynthetically. This study explored the use of bacteriophage P22 virus‐like particles to encapsulate recombinantly expressed bioactive peptides, enabling the production of therapeutically valuable linear and cyclic peptides in Escherichia coli.
Maxim D. Harding   +6 more
wiley   +1 more source

Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold

open access: yesFEBS Open Bio, Volume 15, Issue 3, Page 415-426, March 2025.
Sea stars have remarkable regenerative capabilities. A peptide, KASH2, identified in the biofluid of the common sea star Asterias rubens appears to be involved with the wound‐healing response in the organism. Here, we show the 3D structure of KASH2 adopts a disulfide‐directed β‐hairpin fold, a fold only previously found in arachnids, and does not show ...
Rozita Takjoo   +10 more
wiley   +1 more source

Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail

open access: yesToxins, 2017
Most previous studies have focused on analgesic and anti-cancer activities for the conotoxins identified from piscivorous and molluscivorous cone snails, but little attention has been devoted to insecticidal activity of conotoxins from the dominant ...
Bingmiao Gao   +5 more
doaj   +1 more source

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