Fingerprint Analysis and Comparison of Activity Differences of Crude Venom from Five Species of Vermivorous Cone Snail in the South China Sea [PDF]
Marine DrugsThe South China Sea is rich in cone snail resources, known for producing conotoxins with diverse biological activities such as analgesic, anticancer, and insecticidal effects.
Bingmiao Gao, Shibo Sun
exaly +5 more sources
Non-Peptidic Small Molecule Components from Cone Snail Venoms [PDF]
Frontiers in Pharmacology, 2021 Venomous molluscs (Superfamily Conoidea) comprise a substantial fraction of tropical marine biodiversity (>15,000 species). Prior characterization of cone snail venoms established that bioactive venom components used to capture prey, defend against ...
Zhenjian Lin +14 more
doaj +5 more sources
Screening and Validation of Highly-Efficient Insecticidal Conotoxins from a Transcriptome-Based Dataset of Chinese Tubular Cone Snail [PDF]
Toxins, 2017 Most previous studies have focused on analgesic and anti-cancer activities for the conotoxins identified from piscivorous and molluscivorous cone snails, but little attention has been devoted to insecticidal activity of conotoxins from the dominant ...
Jun-Qing Zhang, Qiong Shi, Bingmiao Gao
exaly +4 more sources
Transcriptomic-Proteomic Correlation in the Predation-Evoked Venom of the Cone Snail, Conus imperialis [PDF]
Marine Drugs, 2019 Individual variation in animal venom has been linked to geographical location, feeding habit, season, size, and gender. Uniquely, cone snails possess the remarkable ability to change venom composition in response to predatory or defensive stimuli.
Paul F Alewood +2 more
exaly +4 more sources
Cone snail species off the Brazilian coast and their venoms: a review and update [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2023 The genus Conus includes over 900 species of marine invertebrates known as cone snails, whose venoms are among the most powerful described so far.
Helena B. Fiorotti +3 more
doaj +2 more sources
Profiling the Paralytic Effects and Lethality of Cone Snail Venom Toxins Using Nanofractionation Analytics with In Vivo Zebrafish Larvae Assays [PDF]
ToxinsThis study presents nanofractionation analytics coupled with in vivo profiling of zebrafish embryo paralysis and lethality in response to toxins in cone snail venoms.
Jeroen Kool +6 more
doaj +2 more sources
The complete mitochondrial DNA genome of a cone snail, Conus betulinus (Neogastropoda: Conidae), from the South China sea [PDF]
Mitochondrial DNA. Part B. Resources, 2021 The complete mitochondrial genome of the tubular cone snail Conus betulinus is presented in this study. The C. betulinus mitochondrial genome was 16,240 bp with 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes ...
Yanling Liao +3 more
doaj +2 more sources
Structural and Functional Analyses of Cone Snail Toxins [PDF]
Marine Drugs, 2019 Cone snails are marine gastropod mollusks with one of the most powerful venoms in nature. The toxins, named conotoxins, must act quickly on the cone snails´ prey due to the fact that snails are extremely slow, reducing their hunting capability ...
Harry Morales Duque +2 more
doaj +2 more sources
A Combined Transcriptomics and Proteomics Approach Reveals the Differences in the Predatory and Defensive Venoms of the Molluscivorous Cone Snail Cylinder ammiralis (Caenogastropoda: Conidae) [PDF]
Toxins, 2021 Venoms are complex mixtures of proteins that have evolved repeatedly in the animal kingdom. Cone snail venoms represent one of the best studied venom systems.
Samuel Abalde +2 more
doaj +2 more sources
Venomics Reveals Venom Complexity of the Piscivorous Cone Snail, Conus tulipa [PDF]
Marine Drugs, 2019 The piscivorous cone snail Conus tulipa has evolved a net-hunting strategy, akin to the deadly Conus geographus, and is considered the second most dangerous cone snail to humans. Here, we present the first venomics study of C.
Mriga Dutt +5 more
doaj +2 more sources