Results 21 to 30 of about 16,099 (174)

Cysteine pattern barcoding-based dataset filtration enhances the machine learning-assisted interpretation of Conus venom peptide therapeutics. [PDF]

open access: yesPLoS ONE
Crude cone snail venom is a rich source of bioactive compounds with significant therapeutic potential. In this study, we conducted a comprehensive analysis of 5,985 cone snail peptides across 82 Conus species to identify unique cysteine (Cys) patterns ...
Rimsha Bibi, Noshaba Qasmi, Sajid Rashid
doaj   +2 more sources

The Biological Role of Conoporins, Actinoporin-like Pore-Forming Toxins from Cone Snails [PDF]

open access: yesToxins
Cone snails are a large group of marine gastropods that produce a complex mixture of toxic compounds to hunt prey and defend against predators. The majority of the venom comprises small toxic peptides named conotoxins, which target membrane receptors. In
Matija Ruparčič   +5 more
doaj   +2 more sources

Combined Proteotranscriptomic-Based Strategy to Discover Novel Antimicrobial Peptides from Cone Snails

open access: yesBiomedicines, 2021
Despite their impressive diversity and already broad therapeutic applications, cone snail venoms have received less attention as a natural source in the investigation of antimicrobial peptides than other venomous animals such as scorpions, spiders, or ...
Anicet Ebou   +4 more
doaj   +1 more source

Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yesEuropean Journal of Taxonomy, 2023
The present work reviews the deep-water cone fauna of New Caledonia and its Economic Exclusive Zone. It is based on the material collected for more than 40 years by oceanographic expeditions in the deep waters surrounding New Caledonia, organized by the
Manuel J. Tenorio, Nicolas Puillandre
doaj   +1 more source

High-throughput prediction and characterization of antimicrobial peptides from multi-omics datasets of Chinese tubular cone snail (Conus betulinus)

open access: yesFrontiers in Marine Science, 2022
Individual cone snail (Conus sp.) contains thousands of bioactive peptides, but there are limited studies on its antimicrobial peptides (AMPs). Here, we investigated AMPs along with AMP-derived genes in the representative Chinese tubular cone snail (C ...
Ruihan Li   +16 more
doaj   +1 more source

Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts. [PDF]

open access: yesAppl Environ Microbiol, 2017
Torres JP   +8 more
europepmc   +2 more sources

Venomics Reveals a Non-Compartmentalised Venom Gland in the Early Diverged Vermivorous Conus distans

open access: yesToxins, 2022
The defensive use of cone snail venom is hypothesised to have first arisen in ancestral worm-hunting snails and later repurposed in a compartmentalised venom duct to facilitate the dietary shift to molluscivory and piscivory.
Jutty Rajan Prashanth   +3 more
doaj   +1 more source

High conopeptide diversity in Conus striatus: Revealed by integration of two transcriptome sequencing platforms

open access: yesFrontiers in Marine Science, 2022
Marine cone snail venoms represent a vast library of bioactive peptides with proven potential as research tools, drug leads, and therapeutics. In this study, a transcriptome library of four different organs, namely radular sheath, venom duct, venom gland,
Yanling Liao   +8 more
doaj   +1 more source

Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins. [PDF]

open access: yesInt J Mol Sci, 2018
O'Brien H   +8 more
europepmc   +2 more sources

Home - About - Disclaimer - Privacy