Results 41 to 50 of about 3,671 (181)

Hormone-like peptides in the venoms of marine cone snails [PDF]

General and Comparative Endocrinology, 2017
The venoms of cone snails (genus Conus) are remarkably complex, consisting of hundreds of typically short, disulfide-rich peptides termed conotoxins. These peptides have diverse pharmacological targets, with injection of venom eliciting a range of physiological responses, including sedation, paralysis and sensory overload.
Robinson, Samuel D., Li, Qing, Bandyopadhyay, Pradip K., Gajewiak, Joanna, Yandell, Mark, Papenfuss, Anthony T., Purcell, Anthony W., Norton, Raymond S., Safavi-Hemami, Helena   +8 more
openaire   +4 more sources

Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea) [PDF]

Molecular Phylogenetics and Evolution, 2014
We present a large-scale molecular phylogeny that includes 320 of the 761 recognized valid species of the cone snails (Conus), one of the most diverse groups of marine molluscs, based on three mitochondrial genes (COI, 16S rDNA and 12S rDNA). This is the first phylogeny of the taxon to employ concatenated sequences of several genes, and it includes ...
Puillandre, N., Bouchet, P., Duda, T.F., Kauferstein, S., Kohn, A.J., Olivera, B.M., Watkins, M., Meyer, C.   +7 more
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Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus

Marine Drugs, 2021
Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels they are attractive drug leads in neuropharmacology.
David A. Armstrong, Ai-Hua Jin, Nayara Braga Emidio, Richard J. Lewis, Paul F. Alewood, K. Johan Rosengren   +5 more
doaj   +1 more source

Mitogenomic phylogeny of cone snails endemic to Senegal

Molecular Phylogenetics and Evolution, 2017
Cone snails attain in Senegal one of their highest peaks of species diversity throughout the continental coast of Western Africa. A total of 15 endemic species have been described, all placed in the genus Lautoconus. While there is ample data regarding the morphology of the shell and the radular tooth of these species, virtually nothing is known ...
Abalde, Samuel, Tenorio, Manuel J., Afonso, Carlos, Zardoya, Rafael   +3 more
openaire   +4 more sources

Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris

Marine Drugs, 2020
Cone snails produce a fast-acting and often paralyzing venom, largely dominated by disulfide-rich conotoxins targeting ion channels. Although disulfide-poor conopeptides are usually minor components of cone snail venoms, their ability to target key ...
Julien Giribaldi, Lotten Ragnarsson, Tom Pujante, Christine Enjalbal, David Wilson, Norelle L. Daly, Richard J. Lewis, Sebastien Dutertre   +7 more
doaj   +1 more source

Prey Shifts Drive Venom Evolution in Cone Snails [PDF]

Molecular Biology and Evolution
Abstract Venom systems are complex traits that have independently emerged multiple times in diverse plant and animal phyla. Within each venomous lineage there typically exists interspecific variation in venom composition where several factors have been proposed as drivers of variation, including phylogeny and diet.
Thomas Lund Koch, Samuel D Robinson, Paula Flórez Salcedo, Kevin Chase, Jason Biggs, Alexander E Fedosov, Mark Yandell, Baldomero M Olivera, Helena Safavi-Hemami   +8 more
openaire   +6 more sources

The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea

Marine Drugs, 2017
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world.
Samuel D. Robinson, Qing Li, Aiping Lu, Pradip K. Bandyopadhyay, Mark Yandell, Baldomero M. Olivera, Helena Safavi-Hemami   +6 more
doaj   +1 more source

Dietary breadth is positively correlated with venom complexity in cone snails [PDF]

BMC Genomics, 2015
Abstract Although diet is believed to be a major factor underlying the evolution of venom, few comparative studies examine both venom composition and diet across a radiation of venomous species. Cone snails within the family, Conidae, comprise more than 700 species of carnivorous marine snails that capture their prey by using a cocktail
Phuong, Mark A, Mahardika, Gusti N, Alfaro, Michael E   +2 more
openaire   +4 more sources

Toxinology of Marine Venomous Snails

Iranian South Medical Journal, 2021
A surprisingly large number of sea snail species are venomous. Cone snail venoms are produced in a lengthy tubular duct from a complex venom gland and form a cocktail of many toxins, particularly conotoxins which have high potency and specificity for ...
Gholam Hossein Mohebbi, Iraj Nabipour
doaj  

Fig. 22 in Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

, 2023
Fig. 22. Bathymetric range and distribution map for Profundiconus zardoyai Tenorio, 2015. Red circles indicate the points where the species was collected.Published as part of Tenorio, Manuel J. & Puillandre, Nicolas, 2023, Revision of the deep-water cone
Tenorio, Manuel J., Puillandre, Nicolas
core   +1 more source