Cone snail venoms are considered an untapped reservoir of extremely diverse peptides, named conopeptides, displaying a wide array of pharmacological activities.
Philippe Favreau +10 more
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Chemical Synthesis and NMR Solution Structure of Conotoxin GXIA from Conus geographus
Conotoxins are disulfide-rich peptides found in the venom of cone snails. Due to their exquisite potency and high selectivity for a wide range of voltage and ligand gated ion channels they are attractive drug leads in neuropharmacology.
David A. Armstrong +5 more
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Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris
Cone snails produce a fast-acting and often paralyzing venom, largely dominated by disulfide-rich conotoxins targeting ion channels. Although disulfide-poor conopeptides are usually minor components of cone snail venoms, their ability to target key ...
Julien Giribaldi +7 more
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Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni [PDF]
© 2008 Lockyer et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Rollinson, D +31 more
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The Venom Repertoire of Conus gloriamaris (Chemnitz, 1777), the Glory of the Sea
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world.
Samuel D. Robinson +6 more
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Toxinology of Marine Venomous Snails
A surprisingly large number of sea snail species are venomous. Cone snail venoms are produced in a lengthy tubular duct from a complex venom gland and form a cocktail of many toxins, particularly conotoxins which have high potency and specificity for ...
Gholam Hossein Mohebbi, Iraj Nabipour
doaj
Bat eyes have ultraviolet-sensitive cone photoreceptors [PDF]
Mammalian retinae have rod photoreceptors for night vision and cone photoreceptors for daylight and colour vision. For colour discrimination, most mammals possess two cone populations with two visual pigments (opsins) that have absorption maxima at short
Josef Ammermüller +23 more
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Conotoxins form a diverse group of peptide toxins found in the venom of predatory marine cone snails. Decades of conotoxin research have provided numerous measurable scientific and societal benefits.
Walden E. Bjørn-Yoshimoto +6 more
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The introduction of marine cone snail species from the coast of the Qeshm Island, contains conotoxin palliative pain in mice [PDF]
Conotoxins are small toxic peptides that are synthesized in cone snail venom ducts. Conotoxins have analgesic effects in models animal. In this study, the analgesic effects with no toxicity of Persian Gulf cone snails, Conus coronatus, and Conus frigidus
Halimeh Rajabi +4 more
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An expressed sequence tag survey of gene expression in the pond snail Lymnaea stagnalis, an intermediate vector of Fasciola hepatica [PDF]
The pond snail Lymnaea stagnalis is an intermediate vector for the liver fluke Fasciola hepatica, a common parasite of ruminants and humans. Yet, despite being a disease of medical and economic importance, as well as a potentially useful comparative tool,
Davison, A., Blaxter, M. L.
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