The mitochondrial genome of the venomous cone snail Conus consors. [PDF]
Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on ...
Age Brauer +9 more
doaj +3 more sources
Venomics-Accelerated Cone Snail Venom Peptide Discovery [PDF]
Cone snail venoms are considered a treasure trove of bioactive peptides. Despite over 800 species of cone snails being known, each producing over 1000 venom peptides, only about 150 unique venom peptides are structurally and functionally characterized ...
Himaya Siddhihalu Wickrama Hewage +1 more
exaly +3 more sources
Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts. [PDF]
Cone snails are biomedically important sources of peptide drugs, but it is not known whether snail-associated bacteria affect venom chemistry. To begin to answer this question, we performed 16S rRNA gene amplicon sequencing of eight cone snail species ...
Margo G. Haygood +2 more
exaly +3 more sources
Characterization of the First Conotoxin from Conus ateralbus, a Vermivorous Cone Snail from the Cabo Verde Archipelago [PDF]
Conus ateralbus is a cone snail endemic to the west side of the island of Sal, in the Cabo Verde Archipelago off West Africa. We describe the isolation and characterization of the first bioactive peptide from the venom of this species.
Jorge L. B. Neves +10 more
doaj +2 more sources
Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor [PDF]
The fish-hunting marine cone snail Conus geographus uses a specialized venom insulin to induce hypoglycemic shock in its prey. We recently showed that this venom insulin, Con-Ins G1, has unique characteristics relevant to the design of new insulin ...
Peter Ahorukomeye +13 more
doaj +2 more sources
Total synthesis and structural characterization of a novel protein scaffold from the snail Biomphalaria glabrata. [PDF]
Abstract Disulfide‐rich miniproteins constitute compact and highly stable scaffolds of growing interest for molecular and structural engineering. Schistosomins are ~80‐residue proteins conserved across gastropods that form a long‐standing orphan family whose structure and biological roles have remained unknown.
Melnyk O +13 more
europepmc +2 more sources
Mitochondrial genome sequencing of a vermivorous cone snail Conus quercinus supports the correlative analysis between phylogenetic relationships and dietary types of Conus species. [PDF]
Complete mitochondrial genome (mitogenome) sequence of a worm-hunting cone snail, Conus quercinus, was reported in this study. Its mitogenome, the longest one (16,460 bp) among reported Conus specie, is composed of 13 protein-coding genes (PCGs), 22 ...
Bingmiao Gao +4 more
doaj +2 more sources
Structures and interactions of insulin-like peptides from cone snail venom [PDF]
Harish Vashisth, Biswajit Gorai
exaly +2 more sources
Based on newly collected material from the Kavieng Lagoon Biodiversity Survey, we describe a new species of cone snail, Conus hughmorrisoni sp. nov., from the vicinity of Kavieng, New Ireland, Papua New Guinea.
Felix Lorenz, Nicolas Puillandre
doaj +3 more sources
Comparative analysis of venom genes in the chromosome-level genomes of two closely related cone snails [PDF]
Background Venom cocktails of cone snails are characterized by their dynamic composition and the rapid evolution of toxin-encoding genes due to various selective pressures.
Ana Herráez-Pérez, Rafael Zardoya
doaj +2 more sources

