Results 51 to 60 of about 238,804 (145)

What explains the invading success of the aquatic mud snail Potamopyrgus antipodarum (Hydrobiidae, Mollusca)? [PDF]

open access: yes, 2008
The spread of non-native species is one of the most harmful and least reversible disturbances in ecosystems. Species have to overcome several filters to become a pest (transport, establishment, spread and impact). Few studies have checked the traits that
Alonso, A., Castro-Diez, P.
core   +1 more source

From venom peptides to a potential diabetes treatment

open access: yeseLife, 2019
Cone snails have evolved a variety of insulin-like molecules that may help with the development of better treatments for diabetes.
Jiří Jiráček, Lenka Žáková
doaj   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Retinal cone photoreceptors of the deer mouse Peromyscus maniculatus : development, topography, opsin expression and spectral tuning [PDF]

open access: yes, 2013
A quantitative analysis of photoreceptor properties was performed in the retina of the nocturnal deer mouse, Peromyscus maniculatus, using pigmented (wildtype) and albino animals.
Glösmann Martin   +8 more
core   +2 more sources

Selective modulation of NaV channel gating counteracts aberrant hyperexcitability and rescues motor function and survival in a model of spinal muscular atrophy

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Spinal muscular atrophy (SMA) is a motor neuron disease caused by SMN1 gene loss, leading to reduced survival motor neuron (SMN) protein and progressive motor neuron degeneration. Although SMN‐restoring therapies improve outcomes, residual disease burden and non‐curative efficacy underscore the need for complementary treatments ...
Fernanda C. Cardoso   +3 more
wiley   +1 more source

Fig. 3 in SNAIL - an interactive computer program for the determination of Central European freshwater gastropods

open access: yes, 2017
Fig. 3: The commputer programm SNAIL (version 1.0) with its eentrance menu (aa) as well as thee main menu (b).Published as part of Sturm, Robert & Snail, 2017, SNAIL - an interactive computer program for the determination of Central European freshwater ...
Snail, Sturm, Robert
core   +1 more source

Impact of past and present management practices on the land snail community of nutrient-poor calcareous grasslands [PDF]

open access: yes, 2007
Nutrient-poor, dry calcareous grasslands in Central Europe harbour an extraordinary high diversity of plants and invertebrates. Consequently, they are of high conservation value.
Boschi, Cristina
core   +1 more source

Conotoxins: Therapeutic Potential and Application

open access: yesMarine Drugs, 2006
The pharmacological variety of conotoxins, diverse peptides found in the venoms of marine cone snails, is well recognized. Venoms from each of the estimated 500 species of cone snails contain 50 to 200 distinct biologically active peptides.
Richard T. Layer, J. Michael McIntosh
doaj   +1 more source

The E‐cadherin‐Wnt‐mir‐994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance

open access: yesCell Proliferation, EarlyView.
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu   +6 more
wiley   +1 more source

Differences in the gene expression profiles of Haemocytes from Schistosome-susceptible and -resistant Biomphalaria glabrata exposed to Schistosoma mansoni excretory-secretory products [PDF]

open access: yes, 2014
During its life cycle, the helminth parasite Schistosoma mansoni uses the freshwater snail Biomphalaria glabrata as an intermediate host to reproduce asexually generating cercariae for infection of the human definitive host.
Rollinson, D   +46 more
core   +2 more sources

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