The introduction of marine cone snail species from the coast of the Qeshm Island, contains conotoxin palliative pain in mice [PDF]
بومشناسی آبزیان, 2019 Conotoxins are small toxic peptides that are synthesized in cone snail venom ducts. Conotoxins have analgesic effects in models animal. In this study, the analgesic effects with no toxicity of Persian Gulf cone snails, Conus coronatus, and Conus frigidus
Halimeh Rajabi +4 more
doaj
Novel conopeptides of the I-superfamily occur in several clades of cone snails [PDF]
, 2004 The I-superfamily of conotoxins represents a new class of peptides in the venom of some Conus species. These toxins are characterized by four disulfide bridges and inhibit or modify ion channels of nerve cells.
Huys, I. +5 more
core +1 more source
The complete mitochondrial genome of Conus quercinus (Neogastropoda: Conidae)
Mitochondrial DNA. Part B. Resources, 2018 The complete mitochondrial genome sequence of cone snail Conus quercinus a kind of worm-hunting sea snails, was performed by next-generation sequencing.
Po-Wei Chen, Wen-Lung Wu, Deng-Fwu Hwang
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Rheotaxis facilitates upstream navigation of mammalian sperm cells [PDF]
, 2014 A major puzzle in biology is how mammalian sperm determine and maintain the correct swimming direction during the various phases of the sexual reproduction process.
Adolphi +37 more
core +3 more sources
From venom peptides to a potential diabetes treatment
eLife, 2019 Cone snails have evolved a variety of insulin-like molecules that may help with the development of better treatments for diabetes.
Jiří Jiráček, Lenka Žáková
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The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) [PDF]
, 2019 Venom is a known source of novel antimicrobial natural products. The substantial, increasing number of these discoveries have unintentionally culminated in the misconception that venom and venom-producing glands are largely sterile environments.
Adams, Rachelle M.M. +13 more
core +1 more source
Hormone-like peptides in the venoms of marine cone snails [PDF]
General and Comparative Endocrinology, 2017 The venoms of cone snails (genus Conus) are remarkably complex, consisting of hundreds of typically short, disulfide-rich peptides termed conotoxins. These peptides have diverse pharmacological targets, with injection of venom eliciting a range of physiological responses, including sedation, paralysis and sensory overload.
Robinson, Samuel D. +8 more
openaire +3 more sources
, 2015 https://scholarworks.sjsu.edu/scientist/1009/thumbnail ...
San Jose State University, College of Science
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Molecular phylogeny and evolution of the cone snails (Gastropoda, Conoidea) [PDF]
Molecular Phylogenetics and Evolution, 2014 We present a large-scale molecular phylogeny that includes 320 of the 761 recognized valid species of the cone snails (Conus), one of the most diverse groups of marine molluscs, based on three mitochondrial genes (COI, 16S rDNA and 12S rDNA). This is the first phylogeny of the taxon to employ concatenated sequences of several genes, and it includes ...
Puillandre, N. +7 more
openaire +5 more sources
Conotoxins: Therapeutic Potential and Application
Marine Drugs, 2006 The pharmacological variety of conotoxins, diverse peptides found in the venoms of marine cone snails, is well recognized. Venoms from each of the estimated 500 species of cone snails contain 50 to 200 distinct biologically active peptides.
Richard T. Layer, J. Michael McIntosh
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