Results 71 to 80 of about 16,099 (174)
The concordance invariant tau in link grid homology [PDF]
We introduce a generalization of the Ozsv\'ath-Szab\'o $\tau$-invariant to links by studying a filtered version of link grid homology. We prove that this invariant remains unchanged under strong concordance and we show that it produces a lower bound for ...
Cavallo, Alberto
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Stretch-activated ion channels in growth cones of snail neurons [PDF]
Using single-channel recording, we show that neurons contain ion channels sensitive to membrane tension. Neurons isolated from the snail, Lymnaea stagnalis, actively rearborized in culture yielding cell bodies and growth cones suitable for patch clamping.
W J, Sigurdson, C E, Morris
openaire +2 more sources
Based on newly collected material from the Kavieng Lagoon Biodiversity Survey, we describe a new species of cone snail, Conus hughmorrisoni sp. nov., from the vicinity of Kavieng, New Ireland, Papua New Guinea.
Felix Lorenz, Nicolas Puillandre
doaj +1 more source
Molecular Phylogeny, Classification and Evolution of Conopeptides [PDF]
Conopeptides are toxins expressed in the venom duct of cone snails (Conoidea, Conus). These are mostly well-structured peptides and mini-proteins with high potency and selectivity for a broad range of cellular targets.
Favreau, P. +4 more
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Venom Insulins of Cone Snails Diversify Rapidly and Track Prey Taxa [PDF]
A specialized insulin was recently found in the venom of a fish-hunting cone snail, Conus geographus Here we show that many worm-hunting and snail-hunting cones also express venom insulins, and that this novel gene family has diversified explosively.
Safavi-Hemami, Helena +8 more
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Dietary breadth is positively correlated with venom complexity in cone snails [PDF]
AbstractAlthough diet is believed to be a major factor underlying the evolution of venom, few comparative studies examine both venom composition and diet across a radiation of venomous species. Cone snails within the family, Conidae, comprise more than 700 species of carnivorous marine snails that capture their prey by using a cocktail of venomous ...
Phuong, Mark A +2 more
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Mining Invertebrate Natural Products for Future Therapeutic Treasure
This review focuses on biologically active entities from invertebrate sources, especially snails. The reader will encounter several categories of compounds from snails including glycosaminoglycans, peptides, proteins (glycoproteins), and enzymes which ...
Youmie Park
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Background Venom cocktails of cone snails are characterized by their dynamic composition and the rapid evolution of toxin-encoding genes due to various selective pressures.
Ana Herráez-Pérez, Rafael Zardoya
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Strategies for the Development of Conotoxins as New Therapeutic Leads
Peptide toxins typically bind to their target ion channels or receptors with high potency and selectivity, making them attractive leads for therapeutic development. In some cases the native peptide as it is found in the venom from which it originates can
Jonathan B. Baell +2 more
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The envenomation of general physiology throughout the last century. [PDF]
Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
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