Results 61 to 70 of about 3,671 (181)

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Fig. 90 in Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yes, 2023
Fig. 90. Bathymetric range and distribution map for Conus (Turriconus) excelsus G.B. Sowerby III, 1908. Red circles indicate the points where the species was collected.Published as part of Tenorio, Manuel J.
Tenorio, Manuel J., Puillandre, Nicolas
core   +1 more source

The E‐cadherin‐Wnt‐mir‐994 Axis Repurposes a Cadherin Switch for Niche Robustness and Germline Stem Cell Maintenance

open access: yesCell Proliferation, EarlyView.
In the Drosophila ovarian niche, an E‐cadherin‐to‐N‐cadherin switch, mediated by Wnt‐mir‐994 signalling, is repurposed to ensure niche resilience. This compensatory mechanism maintains niche integrity and stem cell support upon E‐cadherin loss, revealing a robustness circuit.
Renjun Tu   +6 more
wiley   +1 more source

Fig. 6 in Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yes, 2023
Fig. 6. Bathymetric range and distribution map for Profundiconus estivali (R̂ckel, Richard & Moolenbeek, 1995). Red circles indicate the points where the species was collected.Published as part of Tenorio, Manuel J.
Tenorio, Manuel J., Puillandre, Nicolas
core   +1 more source

Unveiling Gut Homeostasis Disruption in Sepsis: Towards an Integrated Mechanistic and Translational Roadmap

open access: yesCell Proliferation, EarlyView.
Elucidating the contribution of gut‐organ axes will provide new insights for developing combined therapeutic strategies against sepsis‐associated multiple organ dysfunction. ABSTRACT Sepsis, a life‐threatening clinical syndrome precipitated by a maladaptive host response to infection, is associated with substantial morbidity and high mortality rates ...
Yichen Bao   +7 more
wiley   +1 more source

Fig. 56 in Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yes, 2023
Fig. 56. Bathymetric range and distribution map for Conus (Embrikena) pergrandis Iredale, 1937. Red circles indicate the points where the species was collected.Published as part of Tenorio, Manuel J.
Tenorio, Manuel J., Puillandre, Nicolas
core   +1 more source

Conotoxins that Confer Therapeutic Possibilities

open access: yesMarine Drugs, 2012
Cone snails produce a distinctive repertoire of venom peptides that are used both as a defense mechanism and also to facilitate the immobilization and digestion of prey.
John A. C. Archer   +2 more
doaj   +1 more source

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

open access: yesInsect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto   +2 more
wiley   +1 more source

Fig. 84 in Revision of the deep-water cone snail fauna from New Caledonia (Gastropoda, Conoidea)

open access: yes, 2023
Fig. 84. Bathymetric range and distribution map for Conus (Taranteconus) polongimarumai (Kosuge, 1980). Red circles indicate the points where the species was collected.Published as part of Tenorio, Manuel J.
Tenorio, Manuel J., Puillandre, Nicolas
core   +1 more source

One, four or 100 genera? A new classification of the cone snails [PDF]

open access: yesJournal of Molluscan Studies, 2014
We present a new classification for the genus Conus sensu lato (family Conidae), based on molecular phylogenetic analyses of 329 species. This classification departs from both the traditional classification in only one genus and from a recently proposed shell- and radula-based classification scheme that separates members of this group into five ...
Puillandre, N.   +4 more
openaire   +2 more sources

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