Results 81 to 90 of about 238,804 (145)
Strategies for the Development of Conotoxins as New Therapeutic Leads
Marine Drugs, 2013 Peptide toxins typically bind to their target ion channels or receptors with high potency and selectivity, making them attractive leads for therapeutic development. In some cases the native peptide as it is found in the venom from which it originates can
Jonathan B. Baell +2 more
doaj +1 more source
Transactions in GIS, Volume 30, Issue 5, August 2026.ABSTRACT Gathering activities have evolved from survival‐driven practices to predominantly recreational and cultural pursuits, weakening the connection with nature and potentially reducing navigational skills, which may help explain why gathering accounts for 8% of the search operations in Catalonia (Spain). A key focus of this study was the comparison
Albert Martínez +2 more
wiley +1 more source
Wild record of an apple snail in the Waikato River, Hamilton, New Zealand and their incidence in freshwater aquaria [PDF]
, 2011 We report the discovery of a single specimen of a live apple snail Pomacea diffusa Blume 1957 (Ampullariidae: Prosobranchia), from the Waikato River, Hamilton city, central North Island, New Zealand. This species, along with the congeneric P.
Demetras, Nicholas J. +3 more
core +1 more source
Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery
Toxins, 2017 Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than 700 species, have always been one of the focuses for new drug discovery.
Bingmiao Gao +5 more
doaj +1 more source
Food Science &Nutrition, Volume 14, Issue 7, July 2026.Dietary polyphenols and phytochemicals suppress NF‐κB signaling. Mechanistically, by inhibiting IκBα degradation and preventing nuclear translocation of p65/p50 complexes, the polyphenols reduce the expression of pro‐inflammatory and pro‐survival genes, thereby decreasing overall cancer cell survival.
Khuzin Dinislam +3 more
wiley +1 more source
Antiproliferative effect of the Red Sea cone snail, Conus geographus [PDF]
, 2020 Purpose: To investigate the antiproliferative effect of the Red Sea cone snail, Conus geographus, against 4 MCF-7 (breast), MDA-MB-231 (epithelial human breast), HepG2 (hepatocellular) and SKOV-3 (ovarian) cancer cell lines.
Mohammed, Afrah Eltayeb +1 more
core +1 more source
The effect of simulating different intermediate host snail species on the link between water temperature and schistosomiasis risk. [PDF]
, 2014 INTRODUCTION: A number of studies have attempted to predict the effects of climate change on schistosomiasis risk. The importance of considering different species of intermediate host snails separately has never previously been explored.
Booth, Mark +11 more
core +2 more sources
Coupled neuronal oscillators in the snail Lymnaea stagnalis: endogenous cellular properties and network interactions [PDF]
, 1983 Egelhaaf M, Benjamin PR. Coupled neuronal oscillators in the snail Lymnaea stagnalis: endogenous cellular properties and network interactions. Journal of Experimental Biology.
Egelhaaf, Martin ; https://orcid.org/ +1 more
core
Journal of Venomous Animals and Toxins including Tropical Diseases, 2014 Background:Calcium channel blockers such as conotoxins have shown a great potential to reduce brain and spinal cord injury. MVIIC neuroprotective effects analyzed in in vitromodels of brain and spinal cord ischemia suggest a potential role of this toxin ...
Karen M Oliveira +11 more
doaj +1 more source
Distinguishing Drift and Selection Empirically: “The Great Snail Debate” of the 1950s [PDF]
, 2007 Biologists and philosophers have been extremely pessimistic about the possibility of demonstrating random drift in nature, particularly when it comes to distinguishing random drift from natural selection.
Millstein, Roberta L.
core