Results 81 to 90 of about 16,099 (174)
Cone Snails: A Big Store of Conotoxins for Novel Drug Discovery
Marine drugs have developed rapidly in recent decades. Cone snails, a group of more than 700 species, have always been one of the focuses for new drug discovery.
Bingmiao Gao +5 more
doaj +1 more source
Cone snail genome sheds light on venom evolution
<strong> This week in <em> GigaScience </em> we published the genome of the mediterranean cone snail, <em> Lautoconus ventricosus </em> . Cone snails produce a wide variety of powerful toxins and the new chromosome-scale genome assembly opens the door for detailed investigations of their diversity and evolution.
openaire +1 more source
Acute toxicity of atrazine to Oreochromis niloticus fingerlings [PDF]
Acute toxicity of atrazine to Oreochromis niloticus was undertaken to find the lethal concentration (LC) 50 of atrazine using fingerlings. Different concentrations were prepared in mg/L.
Jiya, K.R. +2 more
core
Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates [PDF]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Campbell, L, Jenner, R, von Reumont, B
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Background:Calcium channel blockers such as conotoxins have shown a great potential to reduce brain and spinal cord injury. MVIIC neuroprotective effects analyzed in in vitromodels of brain and spinal cord ischemia suggest a potential role of this toxin ...
Karen M Oliveira +11 more
doaj +1 more source
Novel conopeptides of largely unexplored Indo Pacific Conus sp. [PDF]
Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds having a broad spectrum of ...
D'Souza, L. +9 more
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Multi-view Convolutional Neural Networks for 3D Shape Recognition [PDF]
A longstanding question in computer vision concerns the representation of 3D shapes for recognition: should 3D shapes be represented with descriptors operating on their native 3D formats, such as voxel grid or polygon mesh, or can they be effectively ...
Kalogerakis, Evangelos +3 more
core +3 more sources
Discovery Methodology of Novel Conotoxins from Conus Species
Cone snail venoms provide an ideal resource for neuropharmacological tools and drug candidates discovery, which have become a research hotspot in neuroscience and new drug development. More than 1,000,000 natural peptides are produced by cone snails, but
Ying Fu +5 more
doaj +1 more source
A survey of coccidian infection (Apicomplexa: Eimeriidaea) of freshwater fish in South Africa [PDF]
Fish coccidia, especially Goussia and Eimeria spp., are common and frequent parasites of fish. The majority of the known species has been described from the Eurasian continent.
Avenant-Oldewage, Annemarie +2 more
core
Bioactive Mimetics of Conotoxins and other Venom Peptides
Ziconotide (Prialt®), a synthetic version of the peptide ω-conotoxin MVIIA found in the venom of a fish-hunting marine cone snail Conus magnus, is one of very few drugs effective in the treatment of intractable chronic pain. However, its intrathecal mode
Peter J. Duggan, Kellie L. Tuck
doaj +1 more source

