Results 81 to 90 of about 267,969 (148)

High-resolution picture of a venom gland transcriptome: Case study with the marine snail Conus consors

, 2012
International audienceAlthough cone snail venoms have been intensively investigated in the past few decades, little is known about the whole conopeptide and protein content in venom ducts, especially at the transcriptomic level.
David Piquemal, Favreau, Philippe, Daniel Biass, Stocklin, Reto, Piquemal, David, Ducancel, Frédéric, Sébastien Dutertre, Philippe Favreau, Remm, Maido, Maido Remm, Reto Stöcklin, Dutertre, Sébastien, Terrat, Yves, Biass, Daniel, Frédéric Ducancel, Yves Terrat   +15 more
core   +1 more source

Potential Ancestral Conoidean Toxins in the Venom Cocktail of the Carnivorous Snail Raphitoma purpurea (Montagu, 1803) (Neogastropoda: Raphitomidae)

Toxins
Venomous marine gastropods of the superfamily Conoidea possess a rich arsenal of toxins, including neuroactive toxins. Venom adaptations might have played a fundamental role in the radiation of conoideans; nevertheless, there is still no knowledge about ...
Giacomo Chiappa, Giulia Fassio, Maria Vittoria Modica, Marco Oliverio   +3 more
doaj   +1 more source

Novel Conopeptides of Largely Unexplored Indo Pacific Conus sp.

Marine Drugs, 2016
Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds having a broad spectrum of ...
Eline K. M. Lebbe, Maarten G. K. Ghequire, Steve Peigneur, Bea G. Mille, Prabha Devi, Samuthirapandian Ravichandran, Etienne Waelkens, Lisette D’Souza, René De Mot, Jan Tytgat   +9 more
doaj   +1 more source

Therapeutic potential of cone snail venom peptides (conopeptides)

, 2012
Cone snails have evolved many 1000s of small, structurally stable venom peptides (conopeptides) for prey capture and defense ...
Lewis, Richard J., Vetter, Irina
core   +1 more source

Structures and interactions of insulin-like peptides from cone snail venom. [PDF]

Proteins, 2022
Gorai B, Vashisth H.
europepmc   +1 more source

Uncovering Intense Protein Diversification in a Cone Snail Venom Gland Using an Integrative Venomics Approach

, 2016
Marine cone snail venoms are highly complex mixtures of peptides and proteins. They have been studied in-depth over the past 3 decades, but the modus operandi of the venomous apparatus still remains unclear.
Frédérique Lisacek (1491238), Nicolas Hulo (13954), Philippe Favreau (495664), Reto Stöcklin (1637899), Daniel Biass (1677352), Aude Violette (1677349)   +5 more
core   +1 more source

Characterization of the Conus bullatus genome and its venom-duct transcriptome

BMC Genomics, 2011
Background The venomous marine gastropods, cone snails (genus Conus), inject prey with a lethal cocktail of conopeptides, small cysteine-rich peptides, each with a high affinity for its molecular target, generally an ion channel, receptor or transporter.
Olivera Baldomero M, Bandyopadhyay Pradip K, Hu Hao, Yandell Mark   +3 more
doaj   +1 more source

Investigating Cone Snail Venoms through Proteotranscriptomic Analyses : Application to the Molluskhunter, Cylinder Canonicus

International audienceCone snails are carnivorous marine mollusks, which use a potent neurotoxic venom, for predatory and defensive purposes in their environment [1].
Inguimbert, Nicolas, Ratibou, Zahrmina, Dutertre, Sébastien   +2 more
core   +4 more sources

Biodiversity2Drugs—Renaissance of exploring nature‐derived peptides for GPCR ligand discovery

British Journal of Pharmacology, Volume 182, Issue 16, Page 3691-3694, August 2025.
Christian W. Gruber, Isabel Beets, Pierre‐Luc Boudreault, Vanderlan da S. Bolzani, Jens Carlsson, Pedro A. Fernandes, Michael Freissmuth, Nicolas Gilles, Ulf Göransson, Alexander S. Hauser, Christian Heinis, Jeroen Kool, William D. Lubell, Maria Vittoria Modica, Jana Selent, Jan Tytgat, Eivind A. B. Undheim, The Biodiversity2Drugs Consortium, Christian W. Gruber, Michael Freissmuth, Nicolas Gilles, Marion Chaigneau, Xavier Iturrioz, Pascal Kessler, Philippe Robin, Isabel Beets, Eivind A. B. Undheim, Jeroen Kool, Rob Leurs, Henry Vischer, Jan Tytgat, Steve Peigneur, Kathleen Carleer, Vanderlan da S. Bolzani, Ana Leticia Piros, William Lubell, Pierre‐Luc Boudreault, Alexander S. Hauser, Luuk R. Hoegen Dijkhof, Teemu K. E. Rönkkö, Maria Vittoria Modica, Serena Leone, Giovanna Ponte, Pedro Fernandes, Maria Joao Ramos, Jana Selent, Elizaveta Korchevaya, Tomasz Stepniewski, Jens Carlsson, Israel Cabeza de Vaca, Ulf Göransson, Sunithi Gunasekera, Erik Jacobsson, Christian Heinis, Tao Che, Maurice R. Elphick, Peter J. McCormick, Samuel Robinson, Helena Safavi‐Hemami, Roderich D. Süssmuth, Axel Touchard, Wilfred A. van der Donk, Denise Wootten, Julius Hermes, Johannes Schneider, Ana Leticia Pires, Marin Matic, António J. M. Ribeiro, João Sousa, Joana Ribeiro da Silva, Lauri Urvas, Arun Shukla   +71 more
wiley   +1 more source

Dietary breadth is positively correlated with venom complexity in cone snails [PDF]

, 2016
Although diet is believed to be a major factor underlying the evolution of venom, few comparative studies examine both venom composition and diet across a radiation of venomous species.
Michael E. Alfaro, Alfaro, Michael E, Gusti N. Mahardika, Mark A. Phuong, Mahardika, Gusti N, Phuong, Mark A., Phuong, Mark A, Alfaro, Michael E., Mahardika, Gusti N.   +8 more
core   +1 more source